Liver transplantation followed by autologous stem cell transplantation for acute liver failure caused by AL amyloidosis. Case report and review of the literature
Journal Title: Annals of Hepatology - Year 2016, Vol 15, Issue 4
Abstract
Hepatic involvement in AL amyloidosis may present as acute liver failure. Historically, liver transplantation in these cases has achieved poor outcomes due to progress of amyloidosis and non-hepatic organ damage. In the era of bortezomib treatment, the prognosis of AL amyloidosis has been markedly improved and may also result in better post-transplant outcomes. We present a case of isolated acute liver failure caused by AL amyloidosis, bridged to transplantation with bortezomib and treated with sequential orthotopic liver transplantation (OLT) and autologous stem cell transplantation. The patient is in stable remission 3 years after OLT.
Authors and Affiliations
Mayada Elnegouly, Katja Specht, Heinz Zoller, Edouard Matevossian, Florian Bassermann, Andreas Umgelter
Keywords
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- EP ID EP78606
- DOI 10.5604/16652681.1203163
- Views 136
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