Low birth weight may increase body fat mass in adult women with polycystic ovarian syndrome
Journal Title: International Journal of Reproductive BioMedicine - Year 2016, Vol 14, Issue 5
Abstract
Background: Women engaged with polycystic ovarian syndrome (PCOS), as the commonest endocrine disorder, are known to have a specific type of adiposity. Birth weight is among different contributors reported to be responsible for this diversity. Objective: We aimed to compare the relation between birth weight and body fat mass (BFM)/ body lean mass (BLM) in PCOS and their age and body mass index (BMI) matched normal controls. Materials and Methods: In this case-control study, a total number of 70 reproductive aged women, diagnosed with PCOS and 70 age- BMI matched healthy women without hirsutism and/or ovulatory dysfunction were recruited., control group had no polycystic ovaries in ultrasonographic scans. A detailed history of birth weight was taken and was divided into the following categories: <2,500 (low birth weight, LBW) and 2,500-4,000 (normal birth weight; NBW). Results: Results showed that LBW prevalence was higher in women with PCOS than in controls (19.3% (27) vs. 15.7% (22)). Also body fat and lean mass (BFM, BLM) have increased in adult women with PCOS who were born underweight compared to their normal (19.8±9.05 vs. 12.9±4.5, p=0.001 and 48.9±6.9 vs. 43.2±5.8, p=0.004 respectively). Conclusion: Fetal birth weight influences on the adulthood obesity, BFM and BLM. This impact is different among women with and without PCOS.
Authors and Affiliations
Sonia Minooee, Fahimeh Ramezani Tehrani, Parvin Mirmiran, Fereidoun Azizi
Keywords
Related Articles
- EP ID EP185878
- DOI -
- Views 148
- Downloads 0
Requirements for confirmation of PCR-RFLP results of polymorphisms
NA
The imbalance in expression of angiogenic and antiangiogenic factors as candidate predictive biomarker in preeclampsia
Preeclampsia is an important pregnancy disorder with serious maternal and fetal complications which its etiology has not been completely understood yet. Early diagnosis and management of disease could reduce its potentia...
Kallmann syndrome and deafness: an uncommon combination: A case report and a literature review
Background: Kallmann syndrome (Kal S) is an isolated form of hypogonadotrophic hypogonadism in combination with a defect in smell sensation. Depending on the genetic form of the disease, a number of non-reproductive, non...
Effect of body weight on serum homocysteine level in patients with polycystic ovarian syndrome: A case control study
Background: Polycystic ovarian syndrome (PCOS) represent one of the common endocrine disorders which influence around 8% of reproductive women whom usually suffering from obesity and increase cardiovascular risk. Serum h...
Adenomyosis and its impact on women fertility
Adenomyosis is a widespread disease affecting the reproductive period of women’s life. In the last ten years, different pathogenetic hypotheses have been proposed to explain the initiation and development of the disease....