Lung Fibrosis after Chemotherapy Containing Docetaxel in a Patient Treated for Breast Cancer
Journal Title: International Journal of Cancer Studies & Research (IJCR) - Year 2015, Vol 4, Issue 4
Abstract
Docetaxel has proven effective in many solid tumors, including breast cancer. Hypersensitivity reactions are the most common toxicity associated with docetaxel. However, acute interstitial pneumonia is rarely reported in the literature. We report the case of a woman born in 1969, treated for invasive ductal carcinoma of the left breast and who presented 6 years later with an invasive ductal carcinoma locally advanced in the right breast. Neo-adjuvant chemotherapy based on docetaxel was indicated. Fifteen days after the third course, she had a stage IV dyspnea with a dry cough. Chest radiography showed a bilateral diffuse interstitial infiltrate appearance labeled as an acute interstitial lung disease secondary to docetaxel. The outcome was good after a high dose of corticosteroids. Clinicians should be aware of the risk of interstitial lung disease with docetaxel and introduce a special monitoring of lung function.
Authors and Affiliations
Abdeslam HASSOUNI
Keywords
Related Articles
- EP ID EP198230
- DOI 10.19070/2167-9118- 1500012
- Views 105
- Downloads 0
Anticancer Activity of Acetone Extract of Quercus infectoria Olivier Fagaceae in 1,2 Dimethyl Hydrazine Induced Colon Cancer
Quercus infectoria Olivier (Fagaceae) which contains abundant amount of hydrolysable tannins and traces of gallic acid, ellagic acid and sitosterol is reported to be effective in inflammatory bowel disease. In the presen...
A Case of an Unusually Aggressive Cutaneous Anaplastic Large T-Cell Lymphoma in a Young Patient
Primary Cutaneous Anaplastic Large‑cell Lymphoma (PC‑ALCL) is the second most common cutaneous T‑cell Lym‑ phoma. PCALCL is composed of large cells with an anaplastic, pleomorphic, or immunoblastic cytomorphology, and ex...
Prognostic Value of Artificial Neural Network in Predicting Bladder Cancer Recurrence After BCG Immunotherapy
Background: Artificial neural network (ANN) has been used in medicine to predict either the treatment or the investigative outcomes. The aim of this study was to validate the use of ANN models for predicting recurrence i...
Are there any Dermoscopic Signs of Primary Cutaneous Follicular Center B-cell Lymphoma?
Cutaneous follicular center B-cell lymphoma is an indolent tumor that arise on head or neck. Histology by immunotyping with monoclonal antibodies in frozen or paraffin - embedded tissue is necessary for diagnosis. The tu...
Serum Lipid Fractions and Renal Cell Carcinoma: A Review of Current Literature
Serum Lipid Fractions and Renal Cell Carcinoma Kidney cancer is among the most common human malignancies. In 2008, 273, 518 new cases of kidney cancer were diagnosed throughout the world, representing 2.8% of the worldwi...