Magnesium plasma concentration in haemodialysis patients treated at a single dialysis unit
Journal Title: Postępy Nauk Medycznych - Year 2015, Vol 28, Issue 10
Abstract
Introduction. Mineral disorders are common in dialysed people, but serum magnesiumconcentration is only seldom monitored in this group of patients. The negative consequencesof magnesium deficiency are proved, and in dialysed patients higher concentrationof magnesium correlates with lower mortality and morbidity.Aim. Retrospective examination of plasma concentrations of magnesium determined inadult patients dialysed in one big dialysis unit in Warsaw, and evaluation of some factorsthat could influence or determine its concentration.Material and methods. Retrospective observational study – the results of the firstplasma magnesium concentration measured between January 1, and June 30, 2015 in allpatient on chronic haemodialysis therapy were extracted from the database.Results. We examined 168 patients dialysed with the use of dialysis fluid magnesiumconcentration of 0.5 mmol/l. The mean magnesium plasma concentrationwas 0.87 ± 0.114 mg/dl. In 22 patients (13.09%) mild hypermagnesaemia (not above1.3 mmol/l) and in 3 patients hypomagnesaemia (1.78%) were diagnosed. In 56 out of143 patients (38.5%) with normomagnesaemia, the serum magnesium concentration waslower than 0.83 mmol/l. Serum magnesium concentration was significantly lower in patientspresenting with diabetes.There was statistical correlations between plasma concentration of magnesium andcreatinine (r = 0.47), and nPCR (r = 0.3, p < 0.001), but not with the Kt/V, which suggeststhat nutrition has stronger impact on magnesium concentration than dialysis dose.Conclusions. Since hypomagnesaemia is harmful, and mild hypermagnesaemiaseems to pose no danger to dialysed patients and could be even protective, serummagnesium concentration should be monitored in these patients to avoid magnesiumdeficiency, especially in malnourished patients, those with small muscle mass or withdiabetes.
Authors and Affiliations
Dorota Daniewska, Katarzyna Chmiel-Majewska, Tomasz Żelek, Ryszard Gellert
Keywords
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- EP ID EP77354
- DOI 10.5604/08606196.1189838
- Views 196
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