Magnitude, Pattern and Factors Associated with Ocular Manifestations in Pre-eclampsia/Eclampsia at Mulago National Referral Hospital, Uganda
Journal Title: Journal of Ophthalmology and Advance Research - Year 2021, Vol 2, Issue 1
Abstract
Background: Preeclampsia is a condition where expectant mothers experience a sudden spike in blood pressures and in its severe form of eclampsia they tend to experience seizures. Over 25% of patients with severe pre-eclampsia and 50% of patients with eclampsia have visual symptoms of clinical significance, with 1-3% remaining with irreversible blindness due to involvement of the visual cortex. The ocular changes in preeclampsia usually occur from 20+ weeks of gestation and progress gradually. Hence, early screening of pre-eclampsia mothers can help in timely diagnosis and intervention. With limited data on the ocular conditions of mothers with preeclampsia, this study sought to determine the magnitude, pattern and factors associated with ocular manifestations of preeclampsia/eclampsia mothers at Mulago National Referral Hospital. Methods: This was a descriptive cross-sectional study with 450 consenting pre-eclampsia mothers at Mulago National Referral Hospital from September to December. Ethical Approval was obtained, and pre-tested questionnaires were used to record relevant history and ocular examination findings. Data was cleaned and entered into a computer in EPI-DATA (epidemiology data) and analyzed with STATA 14.0. Results: The prevalence of ocular manifestations was 16.5 % CI (13.3-20.2%). The commonest patterns of ocular manifestations were optic disc edema 19 (26.7%), retinal hemorrhages 17(22.9%) and cotton wool spots 16(21.6%).The factors associated with ocular manifestation of preeclampsia/eclampsia were education (p-value=0.042), sub-urban residence (pvalue=0.045), severe preeclampsia and eclampsia (p-values=0.008 and 0.00), abnormal liver function test (p-value=0.002) and abnormal visual acuity (p-value=0.000). Conclusion: The prevalence of ocular manifestations of pre-eclampsia and eclampsia among women in Mulago National Referral hospital is high and warrants active screening programmes.
Authors and Affiliations
Beatrice M Bako*, Anne Ampaire, Annette Nakimuli, Charity Zalwango, Joanita Nalunjonji, Moses Kasadhakawo
Keywords
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- EP ID EP698929
- DOI http://dx.doi.org/10.46889/JOAR.2021.2106
- Views 80
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