Measurements of Visceral Adiposity, Type-2 Diabetes and Risk for Cardiovascular Disease among Brazilian Men and Women
Journal Title: Journal of Endocrinology and Diabetes - Year 2015, Vol 2, Issue 1
Abstract
Background/aims: To detect a possible association between Visceral Adiposity Index (VAI), Lipid Accumulation Product Index (LAP) and equations to estimate Deep-Abdominal-Adipose- Tissue (DAAT) with type-2 diabetes mellitus and 10-year risk for cardiovascular disease among Brazilian men and women Methods: A cross sectional study was carried out among 99 subjects aged 30 to 80 years without cardiovascular disease. Type- 2 diabetes mellitus was diagnosed according to medical records and 10-year risk for Coronary Heart Disease (CHD) was calculated from Framingham Risk Score (FSR). Anthropometric measurements [weight, height and Waist Circumference (WC)] were made according to standard protocols and biochemical data (total cholesterol, HDLcholesterol and serum triglycerides) were obtained by colorimetric enzymatic method from a certified laboratory. BMI, VAI, LAP and DAAT were calculated and Analysis of Covariance Models (ANCOVA) was performed to detect independent associations. Results: A total of 14 men’s and 85 women’s with an average of 57.4 ±11.9 years were enrolled in the study. Prevalence of type 2-diabetes mellitus was 33.3% according to FSR, 22.2% of the subjects were classified at a higher risk for CHD. After adjustment for confounding factors, type-2 diabetes was associated with DAAT (p = 0.03) and a trend for LAP (p = 0.05). On the other hand, VAI index was significantly higher among subjects with higher risk for CHD (p = 0.01). Conclusions: A positive relation between DAAT and LAP with type-2 diabetes, as well as VAI with risk for cardiovascular disease was found independent of overall obesity. These simple tools for assessment of visceral fat tissue should be considered for clinical practice.
Authors and Affiliations
Angelica Imperico, Aline Marcadenti
Keywords
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- EP ID EP333129
- DOI 10.15226/2374-6890/2/1/00114
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