Meta analysis of traditional Chinese medicine in the treatment of dry eye in recent years
Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 11, Issue 6
Abstract
AIM: To evaluate the traditional Chinese medicine(TCM)for the treatment of dry eye effect in the past five years by using meta analysis method. <p>METHODS: According to the Cochrane evaluation system method, we searched Medline(January 2013 to October 2017), EMbase(2013-2017), Cochrane Library(2017), Wanfang database(2013-2017), VIP(2013-2017), and CNKI(2013-2017)for studies published. We included randomized controlled trials conducted the TCM in the treatment of dry eye. RevMan 5.0 statistical software data extraction and Meta analysis were conducted. <p>RESULTS: A total of 10 studies were identified, nine were from Chinese literature and one was from English literature, of which including 1 229 eyes. Nine of these studies performed BUT measurements at the end of the course of treatment. The results showed a statistically significant difference(<i>P</i><0.00001). Nine studies performed tear flow measurements at the end of the course of treatment and the results showed a statistically significant difference(<i>P</i><0.0001). Two studies performed FL measurements after the end of the course of treatment; the results showed no statistically significant difference(<i>P</i>=0.25). Three studies performed dry eye symptoms after the end of the course of treatment; the results showed that the differences were statistically significant(<i>P</i>=0.0003); the overall efficacy comparison, the difference between the two groups was statistically significant(<i>P</i><0.00001).<p>CONCLUSION: TCM treatment can significantly prolong BUT and increase tear flow, and has more advantages in the treatment of dry eye.
Authors and Affiliations
Qing-Hua Peng
Keywords
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- EP ID EP558504
- DOI 10.3980/j.issn.1672-5123.2018.6.10
- Views 128
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