METHOTREXATE INDUCED STEVENS JOHNSON SYNDROME: A RARE CASE REPORT
Journal Title: Era's Journal of Medical Research - Year 2018, Vol 5, Issue 2
Abstract
Methotrexate (MTX) is a folic acid antagonist with cytotoxic and immunosuppressant activity andwith potent antirheumatic action. It is commonly a first choice Disease modifying antirheumatic drug (DMARD). There were some spurious reports of Adverse Drug Reaction (ADR) by this drug. Here we report a rare occurrence of Stevens-Johnson syndrome (SJS) / Toxic Epidermal Necrolysis (TEN) after the use of Methotrexate. Naranjo score for this adverse drug event was six, thereby making it a probable ADR. Symptomatic management of the patient was done and the offending drug was withdrawn. We are presenting this case to highlight the serious adverse reactions possible from a routinely prescribeddrug.
Authors and Affiliations
Surabhi Arora, Afroz Abidi, Fariha Fatima, Roohana Hasan, Darakhshan Rizvi, Anupriya Thadani
Keywords
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- EP ID EP622355
- DOI 10.24041/ejmr2018.95
- Views 153
- Downloads 0
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