Microperimetry – A New Tool for Assessing Retinal Sensitivity in Macular Diseases

Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 7

Abstract

Introduction: Macular disease is the leading cause of low vision in the Western world. Drusen and pigmentary irregularities are common among the rural Northern Indian population. The disease process leads to loss of central vision, metamorphopsia, macropsia or micropsia and colour vision defect. Aim: To study the retinal sensitivity changes in macular diseases using microperimetry. Materials and Methods: It was an observational study, conducted in the Department of Ophthalmology at a rural tertiary care hospital. This study was started from December 2014 until June 2016, in all patients with macular disease above the age of 20 years attending the outpatient department. Microperimetry was done for 84 eyes of 52 patients with macular disease. Mean retinal Sensitivity (MS) and fixation stability was evaluated. The statistical analysis of mean retinal sensitivity, central 2˚ and 4˚ fixation was done by calculating the mean and standard deviation using 95% confidence interval. Results: The range of age was between 20-81 years. Majority were 32 males (62%) and 20 females (38%). Out of the 84 eyes studied, majority of the macular disease were Age-Related Macular Degeneration (AMD) (50%). Rest 50% were other macular diseases. The mean retinal sensitivity (dB) shown by microperimetry was 10.83 in AMD, 9.12 in Cystoid Macular Oedema (CME), 10.34 in Epiretinal Membrane (ERM), 10.74 in Pigment Epithelial Detachment (PED), 8.96 in Central Serous Chorioretinopathy (CSCR), 6.43 in macular dystrophy, 7.15 in Lamellar Hole (LMH), 9.8 in Pseudomacular Hole (PMH), 3 in geographic atrophy, 11.1 in macular telangiectasia, 5.6 in Berlin oedema, 12.3 in macular scar and 15.2 in haemorrhage in macula. The study showed 64% of the eyes had stable 2˚ central fixation, 35% had relatively unstable fixation and 1% had unstable fixation. No significant correlation between retinal sensitivity and retinal thickness in AMD was found. Conclusion: This study shows that microperimetry can be a useful tool for objective evaluation of macular function and progression of the disease.

Authors and Affiliations

Memota Laishram, Krishnagopal Srikanth, AR Rajalakshmi, Swathi Nagarajan, G Ezhumalai

Keywords

Related Articles

Prevalence and Molecular Characterisation of Methicillin-Resistant Coagulase Negative Staphylococci (MR-CoNS) Isolated from Nasal Carriers of End Stage Renal Disease Patients- A Prospective Study

ABSTRACT Introduction: Patient-to-patient transmission of resistant strains has caused a rapid increase in the prevalence of antimicrobial resistance in recent years. Infection has become a major cause of morbidity and i...

Successful Orthodontic and Periodontic Management of Impacted Central Incisor with Compromised Labial Bone

ABSTRACT Normal eruption of teeth is considered a critical phase for the development of hard and soft tissue apparatus of the craniofacial system. Disturbance in tooth eruption, in general, may lead to delay of eruption...

Conservative Management of Intraperitoneal Urinary Bladder Perforation with Enterovesical Fistula

ABSTRACT Surgical repair is usually done in intraperitoneal bladder perforation, whereas in genitourinary trauma reports of conservative management exist. We hereby, present a case of an old man with carcinoma prostate h...

An Assessment of Osteoporotic Conditions among Users and Non-Users of Warfarin: A Case-Control Study

Introduction: Warfarin is an oral anticoagulant which is associated with a decrease in Bone Mass Density (BMD). Aim: The study aimed to explore the prevalence of osteoporosis conditions in Malaysians with chronic warfari...

Pleiotropic Effects of Losartan in Hypertensive Patients with Dyslipidemia

Introduction: In essential hypertension, the comorbidity of dyslipidemia is very common. In addition to hypertension, dyslipidemia is linked to cardiovascular disease, stroke and decline in renal function. Unlike other a...

Download PDF file
  • EP ID EP355541
  • DOI 10.7860/JCDR/2017/25799.10213
  • Views 88
  • Downloads 0

How To Cite

Memota Laishram, Krishnagopal Srikanth, AR Rajalakshmi, Swathi Nagarajan, G Ezhumalai (2017). Microperimetry – A New Tool for Assessing Retinal Sensitivity in Macular Diseases. Journal of Clinical and Diagnostic Research, 11(7), 8-11. https://www.europub.co.uk/articles/-A-355541