Microwave-assisted synthesis of phenanthro[9, 10-d]imidazole derivatives under solvent-free and one pot conditions
Journal Title: Journal of Medicinal and Chemical Sciences - Year 2020, Vol 3, Issue 0
Abstract
Phenanthro[9, 10-d]imidazole derivatives were synthesized with the combinations of phenanthroquinone and benzealdehyde derivatives in the presence of ammonium acetate. The microwave-assisted protocol was investigated under solvent-free condition for 2 min (400 w). The structure of all products was studied by IR and 1HNMR Spectroscopy. Excellent yields, short reaction times, simplicity of operation and easy separation are the advantages of this technique.
Authors and Affiliations
Forough Cheldavi, Mohammad Kazem Mohammadi
Triterpenoid Saponins from the Stem Bark of Xeromphis nilotica (Rubiaceae)
Two new triterpenoid saponins, named, 3-O-β-D-glucopyranosyl (1→3)-Olean-12-ene-19, 23-diol 1 and 3-O-{O-α-L-rhamno-pyranosyl-(1→3)-O-[-O-β-D-glucopyranosyl-(1→3)]-β-D-gluco-pyranosyl}-pomolic acid were isolated from th...
Development and validation of RP-HPLC method for simultaneous estimation of three components in cream formulation used in hemorrhoids disease
Developing a single analytical method for the determination of individual drug from a multidrug composition is a very difficult task. The present work describes a simple, rapid, precise reverse phase chromatographic meth...
Microwave-assisted synthesis of phenanthro[9, 10-d]imidazole derivatives under solvent-free and one pot conditions
Phenanthro[9, 10-d]imidazole derivatives were synthesized with the combinations of phenanthroquinone and benzealdehyde derivatives in the presence of ammonium acetate. The microwave-assisted protocol was investigated und...
Ultrasound assisted synthesis of N-aryl indole under multi-site phase-transfer catalyst: A kinetic study
The ultrasound assisted preparation of 1-benzyl-1-indole (arylation) from the reaction of benzyl chloride (BC) and indole was carried out successfully using solid sodium hydroxide and catalyzed by multi-site phase-transf...
Considering different kinds of gasoline unit catalysts
The aim of this study is to investigate naphtha Gasoline unit catalysts. In two-factor catalysts, platinum or palladium was used as the active metal on the base alumina chloride, zirconia, and zeolite. Considering the fa...