Molecular pathological changes of cataract
Journal Title: Eye Science (Yanke Xuebao) - Year 2021, Vol 36, Issue 8
Abstract
Cataract is the main cause of blindness worldwide. The normal crystalline lens is a transparent biconvex disc, with highest protein content in all human tissues. The lens is composed of capsule, lens epithelial cells, lens fiber and zonular ligment. Cataract is a decrease in the transparency of the lens, which is characterized by opacity. In recent years, with the rapid development of molecular biology, epigenetics, immunology and organic chemistry, researchers have conducted a large number of studies on the molecular basis of genetic or targeted therapy of cataract. It is important to know the molecular pathology of cataract, which is the basis of precise diagnosis and treatment of cataract.
Authors and Affiliations
Min JI, Huaijin GUAN
Clinical characteristics and therapeutic effect of 46 cases of bilateral retinoblastoma
[Objective:] To analyze the clinical characteristics and therapeutic effect of 46 patients with bilateral retinoblastoma (RB). [Methods:] The clinical data of 46 patients with bilateral retinoblastoma who received intrav...
Analysis of influencing factors and General Well-Being Schedule evaluation in early-postoperative cataract patients during the COVID-19 epidemic
[Objective:] To evaluate the general well-being and its associated factors for the early-postoperative patients with different types of cataract during the epidemic of corona virus disease 2019 (COVID-19), and to provide...
Macular edema after cataract surgery in a patient with microspherophakia: a case report
Microspherophakia (MSP) is a rare congenital zonular dysplasia characterized by increased anteroposterior lens thickness and reduced equatorial diameter, resembling a spherical shape. The related ocular manifestations of...
Neuroprotective effect of tafluprost in glaucoma treatment and its molecular mechanism
Glaucoma is characterized by the progressive degeneration and loss of retinal ganglion cells (RGC) and their axons, making it one of the most common causes of vision loss. Although the exact underlying mechanisms remain...
Research progress in molecular omics of neovascular age-related macular degeneration
Age-related macular degeneration (AMD) is one of the leading causes of vision loss in elderly population. Among its subtypes, neovascular AMD (nAMD) has become a global focus in ophthalmological research due to its rapid...