MULTIPARTICULATE DRUG DELIVERY SYSTEM: PELLETIZATION THROUGH EXTRUSION AND SPHERONIZATION
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 2
Abstract
Pharmaceutical invention and research are increasingly focusing on delivery systems which enhance desirable therapeutic objectives while minimising side effects. Recent trends indicate that multiparticulate drug delivery systems are especially suitable for achieving controlled or delayed release oral formulations with low risk of dose dumping, flexibility of blending to attain different release patterns as well as reproducible and short gastric residence time. Pelletization is a technique used to prepare fine powders into pellets used as multiparticulate drug delivery systems. There are different pelletization techniques used to prepare pellets. Extrusion and spheronization is one of them used to prepare pellets drug loaded beads/pellets for extended release or sustained release oral formulations such as tablets and capsules.
Authors and Affiliations
Anshuli Sharma, Sandhya Chaurasia
Keywords
Related Articles
- EP ID EP120122
- DOI -
- Views 108
- Downloads 0
ASSESSMENT OF DISEASE ORIENTED DEPRESSION IN BREAST CANCER PATIENT
Depression is a common symptom in cancer patients, which is difficult to be detected and consequently to be treated. It deteriorates over the course of cancer treatment, persists long after the end of therapy and influen...
ASSESSMENT OF OLIGOSPERMIA WITH SPECIAL REFERENCE TO SHUKRADUSHTI
Diagnosed Patients of Oligospermia were taken for Semen analysis for comparison of Shukradushti with vitiation of Doshas. The assessment of Oligospermia with Ayurvedic Shukradushti was analysed by modern equipment. As pe...
ANTIARTHRITIC ACTIVITY OF MILK EXTRACT OF SEMECARPUS ANACARDIUM NUT
The present study is aimed to evaluate the anti-arthritic activity of milk extract of Semecarpus anacardium nut using inhibition of protein denaturation model and human red blood cell Membrane stabilization model. Diclof...
STUDY OF EFFECT OF BHASTRIKA PRANAYAMA ON PULMONARY FUNCTION
Yogic practices can be used as psycho-physiological stimuli to increase in physiological functions and human performance. Yoga breathing or Pranayama is the science of breath control. Rapid succession of forcible expulsi...
ANTIMICROBIAL ACTIVITY OF FICUS RACEMOSA L. AND CISSAMPELOS PAREIRA L. VAR. HIRSUTA (DC) FORMAN., AGAINST E. COLI, P. AEROGINOSA, S. AUREUS AND B. SUBTILIS
The present work was designed to assess the antimicrobial activity of the methanolic extracts of the bark of Ficus racemosa L. and root of Cisampelos pareira L. var. hirsuta (DC) Forman. The antimicrobial activity of the...