Natural products as a crucial source of anti-inflammatory drugs: recent trends and advancements
Journal Title: Traditional Medicine Research - Year 2019, Vol 4, Issue 5
Abstract
Natural active molecules are key sources of modern innovative drugs. Particularly, a great amount of natural active molecules have been reported to possess promising therapeutic effects on inflammatory diseases, including asthma, rheumatoid arthritis, hepatitis, enteritis, metabolic disorders and neurodegenerative diseases. However, these natural active molecules with various molecular structures usually exert anti-inflammatory effects through diversiform pharmacological mechanisms, which is necessary to be summarized systematically. In this review, we introduced the current major anti-inflammatory natural active molecules based on their chemical structures, and discussed their pharmacological mechanisms including anti-inflammatory molecular signaling pathways and potential target proteins, which providing a referential significance on the development of novel anti-inflammatory drugs, and also revealing new therapeutic strategies for inflammatory diseases.
Authors and Affiliations
Yan-Hang Wang, Ke-Wu Zeng
Keywords
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- EP ID EP49636
- DOI 10.12032/TMR20190225103
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