CLINICAL EVALUATION OF CLONIDINE AS AN ADJUNCT TO CAUDAL ROPIVACAINE IN PEDIATRIC INFRAUMBILICAL SURGERIES

Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 37

Abstract

  [b]BACKGROUND[/b]: The addition of clonidine as an adjuvant has allowed the use of lower concentration of the local anaesthetic for achieving the same level of anaesthesia but with the prolonged duration of analgesia which increases the margin of safety and reduces the incidence of unwanted motor blockades. With these facts in mind we undertook the study to compare the analgesic properties of 0.25% ropivacaine with the addition of clonidine (1µg/kg) to that of ropivacaine 0.25% following caudal administration in children. [b]METHODS[/b]: After approval from ethical committee 60 children of age 1-10 yrs of ASA grade I or II undergoing elective sub umbilical surgeries were selected for the study. We gave caudal block with 0.25% ropivacaine 1ml/kg+1ml normal saline for group R or 0.25% ropivacaine 1ml/kg + clonidine 1microgram/kg+1ml normal saline to make volume 1ml for group C. To perform caudal block all patient received IV injection glycopyrolate- 0.01mg/kg, IV injection midazolam- 0.1mg/kg and IV Injection ketamine-1mg/kg. Hemodynamic parameters were observed before, during and after the surgical procedure. Quality of surgical anesthesia & requirement of supplemental midazolam/ketamine were also noted. Duration of Post-operative analgesia, pain scores, level of sedation and side effects if any were looked for and duly recorded. [b]RESULT[/b]: Duration of analgesia in group R was 6.45±0.52 hrs. and in group C was 13.01±0.89hrs i.e. significantly prolonged in group C (P<0.0001). Post-operative pain score and sedation score were also significantly better in group C (P<0.0001). The quality of surgical analgesia was also significantly excellent in group C. Other vital parameters were not statistically significant in both the groups.[b] CONCLUSION: [/b]Ropivacaine (0.25%) with clonidine (1μg/kg) in caudal block showed prolong duration of analgesia as well as better quality of surgical anaesthesia than plain ropivacaine (0.25%) in pediatric patients without any significant side effects.

Authors and Affiliations

Urmila Keshari, Sonal Awasya, Tripti Vatsalya

Keywords

Related Articles

AN ECHOCARDIOGRAPHIC ASSESSMENT OF RIGHT VENTRICULAR FUNCTION IN INFERIOR WALL MYOCARDIAL INFARCTION UNDERGOING PRIMARY PTCA VS. PTCA WITHIN ONE MONTH OF INDEX EVENT- A FOLLOW-UP STUDY

BACKGROUND Risk of shock, arrhythmia and death due to Inferior Wall Myocardial Infarction (IWMI) is higher in the presence of Right Ventricular Myocardial Infarction (RVMI). RVMI along with IWMI (relative risk 3.0) usual...

SURGICAL EXCISION OF EYEBALL- ARE ALL CASES UNAVOIDABLE?

BACKGROUND Surgical removal of eyeball is not very uncommon. It is done for different indications like tumours, inflammations, injury, etc. Some of these excisions were inevitable, but many are having modifiable courses....

A CLINICAL STUDY OF HEART DISEASE IN PREGNANCY AT GOVERNMENT MATERNITY HOSPITAL

BACKGROUND 1Heart disease is the fourth most common cause of maternal death and the most common indirect cause of maternal mortality. The physiological adaptation of normal pregnancy can induce symptoms and alter clinica...

A STUDY ON MAGNETIC RESONANCE IMAGING FINDINGS IN CHILDHOOD EPILEPSY

BACKGROUND Epilepsy is the most common brain disorder during childhood and it may be associated with serious conditions. Early recognition and treatment is essential for best possible outcome. MRI is the modality of choi...

STUDY OF ADJUSTMENT IN PATIENTS WITH INVOLUNTARY MOVEMENT DISORDERS

BACKGROUND Adjustment disorder is a short-term maladaptive reaction to a psychosocial stressor. The reaction is more severe than would normally be expected and can result in significant impairment in social, occupational...

Download PDF file
  • EP ID EP90210
  • DOI 10.14260/jemds/2015/933
  • Views 138
  • Downloads 0

How To Cite

Urmila Keshari, Sonal Awasya, Tripti Vatsalya (2015).   CLINICAL EVALUATION OF CLONIDINE AS AN ADJUNCT TO CAUDAL ROPIVACAINE IN PEDIATRIC INFRAUMBILICAL SURGERIES. Journal of Evolution of Medical and Dental Sciences, 4(37), 6420-6428. https://www.europub.co.uk/articles/-A-90210