EVALUATION OF MEAN PLATELET VOLUME AS A PROGNOSTIC MARKER IN TYPE II DIABETES MELLITUS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 19
Abstract
[b]BACKGROUND:[/b] Diabetes mellitus (DM) is both metabolic disorder and a major worldwide health problem because of its high prevalence and mortality. The prevalence of cardiovascular complication of type II DM may be associated with glycosylated hemoglobin (HbA1c) and mean platelet volume (MPV). [b]AIM[/b]: 1. To investigate if platelets were activated in diabetes and its associated complications by measuring the MPV in diabetics compared to non-diabetics. 2. To determine the correlation of MPV among diabetics with Fasting blood Glucose levels (FBS), HbA1c, duration and complications of diabetes respectively. [b]MATERIALS AND METHODS[/b]: A prospective study was carried on 200 diabetic patients and 200 control subjects. Both the groups underwent thorough clinical examination in terms of complications and duration of diabetes and laboratory investigations was performed. Laboratory investigations such as haemoglobin (Hb), white blood count (WBC), platelet count (Plt), MPV, FBS and HbA1c values of the participants were recorded. [b]RESULTS[/b]: We could find significant increase in MPV among diabetics (8.83 ±0.72 fl) when compared to non-diabetics (7.62±0.47 fl) with a P value of 0.001. MPV showed a strong positive correlation with fasting blood glucose level, HbA1c levels, duration and complication of DM. [b]CONCLUSION[/b]: MPV is associated with increase in FBS, HbA1c, duration and complications associated with DM. Therefore, MPV might be a useful prognostic marker of cardiovascular complications in patients with type II DM.
Authors and Affiliations
Navya B. N, Dhanalakshmi D. P, Vivek T. G, Kariappa T. M
PLASMA CELL LEUKAEMIA- AN AGGRESSIVE PLASMA CELL DYSCRASIA
Plasma cell leukaemia is a rare and aggressive variant of plasma cell myeloma having poor outcome. Some improvements in outcome have been made in recent years with newer therapies and stem cell transplantation. Plasma ce...
SURVEY OF PATIENTS ATTITUDE ABOUT ANAESTHESIA AND ANAESTHESIOLOGIST- A PRELIMINARY EVALUATION IN A RURAL HOSPITAL OF NORTH BENGAL
BACKGROUND Image of anaesthesia and anaesthesiologist in the eyes of patients is variedly reported in literature and mostly poor in developing countries. We often realised this underestimation of our risky task, inadequa...
SECONDARY INFECTIONS IN SWINE FLU
[b] BACKGROUND AND OBJECTIVE[/b]: Swine influenza is respiratory disease of pigs caused by type A influenza virus that causes regular outbreak in pigs. Human to human transmission occurs. Some people develop sev...
COMPUTED TOMOGRAPHIC EVALUATION OF PATIENTS PRESENTING WITH MALIGNANT RENAL MASSES
BACKGROUND The term renal mass includes a large number of expansile entities, which are aggregates of non-functional renal parenchyma. Renal masses can be neoplastic, non-neoplastic or normal variants. Aims and Objective...
A COMPARATIVE STUDY TO EVALUATE THE EFFICACY AND SAFETY OF VALACYCLOVIR AND FAMCYCLOVIR IN THE MANAGEMENT OF HERPES ZOSTER IN A TERTIARY CARE HOSPITAL IN PUDUCHERRY
[b]OBJECTIVE:[/b] The objective of this study was to compare the efficacy and safety of Valacyclovir and Famcyclovir in the management of Acute Herpes Zoster.[b] MATERIALS AND [/b] [b]METHODS: [/b]Relevant data were...