A Prospective Study of Nonsuppurative Complications of Streptococcal Pharyngitis
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2016, Vol 6, Issue 1
Abstract
Objective: Group A Streptococci (GAS) are the most important bacterial cause of pharyngitis. Antibiotic therapy can be prescribed and failure to treat it is associated with suppurative and nonsuppurative complications. Nonsuppurative complications occur after a latency period of a few weeks and include acute rheumatic fever, scarlet fever, streptococcal toxic shock syndrome, acute glomerulonephritis, and pediatric autoimmune neuropsychiatric disorder associated with group A streptococci. The aim of this study is to investigate the frequency of nonsuppurative complications in properly treated children with GAS pharyngitis. Methods: We investigated the frequency of nonsuppurative complications in 1030 proven GAS pharyngitis patients between 5 and 15 years old, who were properly treated by a prospective observational study. All patients diagnosed with GAS pharyngitis were followed up prospectively using a standard form for six months made by monthly phone calls. Results: All the isolates recovered from the patients were susceptible to penicillin. Twentyseven (2.6%) patients developed scarlet fever. No other nonsuppurative complications occured in our patient cohort. Conclusions: Penicillin remains the drug of choice for treatment of GAS pharyngitis. The rate of nonsuppurative complications of GAS pharyngitis has decreased significantly in the antibiotic era. J Microbiol Infect Dis 2016;6(1): 8-11 Key words: Group A Streptococci, nonsuppurative complications, scarlet fever
Authors and Affiliations
Mesut Yılmaz, Mehmet Gündüz, Ferhat Arslan, Abdülkadir Yıldız, Nigar Gümrükçüoğlu, Zehra Aras, Ece Kaya, Ceren Gülpınar, Arzu Dobral, Ali Mert
Keywords
Related Articles
- EP ID EP143726
- DOI 10.5799/ahinjs.02.2016.01.0206
- Views 126
- Downloads 0
Soft Tissue Abscess due to Eikenella corrodens after Human Bite
Eikenella corrodens is found in oral, gastrointestinal and genitourinary normal flora. Eikenella species have been shown to cause serious human infections such as head-neck infection, pulmonary infection, arthritis...
Prognostic value of mean platelet volume and neutrophil to lymphocyte ratio in patients with Crimean-Congo Hemorrhagic Fever
Objective: Crimean-Congo hemorrhagic fever (CCHF) virus, a Nairovirus within the family Bunyaviridae, causes severe disease in humans. Pancytopenia, organ failures and disseminated intravascular coagulation may occur as...
Fosfomisinin klinik izolatlara karşı in vitro etkinliği
Amaç: Fosfomisin komplike olmayan üriner sistem enfeksiyonlarının tedavisinde alternative bir ilaçtır. Bu çalışmanın amacı fosfomisinin in vitro etkinliğini, metisiline dirençli Staphylococcus aureus (MRSA), metisiline d...
Thyroid disorders associated with hepatitis C or interferon based therapies
Several extrahepatic diseases have been associated with chronic hepatitis C virus (HCV) infection (i.e. hematologic diseases, renal disease, dermatologic conditions). It has also been shown that HCV infection is associa...
Investigation of Naturally Acquired Antibody to Haemophilus influenzae Type b Polysaccharide in China
In a word, although this investigation having relatively less scope, however, for public health policy makers we recommend a range which may lead to decrease the spread of Hib infection.