A PROSPECTIVE STUDY OF PHARMACOLOGICAL PROPHYLAXIS OF DEEP VEIN THROMBOSIS IN ARTHROPLASTY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2014, Vol 3, Issue 18
Abstract
[b]BACKGROUND: [/b]Joint replacement surgeries were associated with significant risk of deep vein thrombosis further leading to complications like pulmonary embolism, a need for prevention of complications by using DVT prophylaxis among Indian patients.[b] OBJECTIVE[/b]: The risk of DVT & pulmonary embolism following joint replacement surgeries were largely studied in western countries whereas the same following arthroplasty was studied to a lesser extent in India. To find out the efficacy of Pharmacological Prophylaxis against DVT (Deep Venous Thrombosis) or PE (Pulmonary Embolism).To find out incidence of DVT (Deep Venous Thrombosis) or PE (Pulmonary Embolism) Despite prophylaxis. [b]METHODS[/b]: prospective study of pharmacological prophylaxis of deep venous thrombosis in arthroplasty using low molecular weight heparin and aspirin .patients were investigated pre & post operatively with Doppler study for evidence of venous thrombosis. [b]RESULTS: [/b]Distal DVT was found in two patients who underwent THR; there was no case of proximal DVT with THR and TKR. No DVT was detected in any patient who had undergone TKR preoperatively or postoperatively. [b]CONCLUSION[/b]: We believe that though there is enough evidence in the Western literature to advocate routine thromboprophylaxis for patients undergoing total joint replacement and surgery for fractures of lower limb, there is not yet enough evidence to justify the same for Indian patients undergoing major lower limb surgery. A duplex sonography should be preferably carried out on all the elderly and high-risk patients undergoing total joint arthroplasty, Trials involving a larger number of patients in future are required
Authors and Affiliations
Gopalakrishna K. G, Diwakar T. N, Manjunath K. S, Annappaswamy
Keywords
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- EP ID EP148683
- DOI 10.14260/jemds/2014/2506
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