A REVIEW ON BIOANALYTICAL TECHNIQUES
Journal Title: Int J of Preclin & Pharm Res - Year 2012, Vol 2, Issue 1
Abstract
ABSTRACT Quantitative determination of active pharmaceutical ingredient and its degradative products in biological fluids is a challenging task for an analyst due to difficulties and uniqueness of the sample. A systematic study of pharmaceutical products on human subjects whether patients or non-patient volunteers in order to discover or verify the clinical, pharmacological (including pharmacodynamics/ pharmacokinetics), adverse effects, with the object of determining their safety or efficacy and correcting plasma level with therapeutic action. Keywords: Bioanalytical method, Recent Analytical Techniques, LC-MS/MS.
Authors and Affiliations
*M. Sekar Babu
MICROSPONGES: A NOVEL DRUG DELIVERY SYSTEM FOR CONTROLLED DELIVERY OF TOPICAL DRUGS
ABSTRACT Even though possess several advantages topical formulations have some drawbacks such as the need to contain high concentrations of active agents for effective therapy due to the low efficiency of deliver...
SUPER CRITICAL FLUID CHROMATOGRAPHY: AN OVERVIEW
ABSTRACT Supercritical Fluid Chromatography (SFC) is a form of normal phase chromatography, first used in 1962.SFC typically utilizes carbon dioxide as the mobile phase; therefore the entire chromatographic flow...
UTILITY OF ORAL AND VAGINAL MISOPROSTOL IN THE INDUCTION OF LABOUR: A COMPARATIVE STUDY
ABSTRACT This study was conducted to compare the efficiency and safety of oral (50 μg) and vaginal (25 μg) misoprostol for labour induction. In this study one Hundred patients with indications for labour inductio...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF SIMULTANEOUS ESTIMATION OF RUPATADINE FUMARATE AND MONTELUKAST SODIUM BY RP-HPLC
ABSTRACT A sensitive, selective and precise high performance liquid chromatographic method has been developed and validated for the simultaneous determination of Rupatidine fumarate and Montelukast sodium in tabl...
FLASH CHROMATOGRAPHY: AN OVERVIEW
ABSTRACT Flash chromatography is a rapid purification technique used to purify compounds of wide ranging polarity; often reaction mixtures, where the target (synthesized) molecule must be separated from excess r...