A REVIEW ON GENE SILENCING
Journal Title: International Journal of Pharmaceutical Development & Technology - Year 2015, Vol 5, Issue 1
Abstract
ABSTRACT Gene silencing is a epigenetic term which means the expression of a particular gene is reduced by genetic engineering techniques using mechanism like DNA methylation and RNA interference. This technique if used perfectly and encouraged, can answer many mutational disorders which are incurable at present. These also give scope for us to explore into a new world of many unknown genes which have vital functions in the body. Even botanical silencing can be done to increase their resistance towards the attack of virus and many other harmful agents. It was found to be productive in combating against many cancers, viral diseases,bacterial infections and several mutational disorders. Research works are being done in institutes like the Scripps institute, California is undertaking studies on silencers which are helpful in treatment of cancer, rheumatoid arthritis, hemophilia etc. The national institute of health, Maryland, America are trying to implement silencers in Parkinsonism. Gene silencing in plants is being done in Howard Hughes medical institute. Keywords: America, DNA methylation, California.
Authors and Affiliations
S. V. S. S. Ravi Teja*
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