CHRONIC KIDNEY DISEASE-MINERAL BONE DISORDER IN DIABETES MELLITUS PATIENTS
Journal Title: Romanian Journal of Diabetes Nutrition and Metabolic Diseases - Year 2012, Vol 19, Issue 1
Abstract
Diabetes mellitus (DM) and chronic kidney disease (CKD) are two diseases with increasing prevalence and adverse outcomes that represent an international health problem. Chronic kidney disease- mineral and bone disorder (CKD-MBD) is defined as a systemic disorder of mineral and bone metabolism due to CKD manifested by either one or a combination of the following: abnormalities of calcium, phosphorus, PTH, or vitamin D metabolism; abnormalities in bone turnover, mineralization, volume, linear growth, or strength and vascular or other soft-tissue calcification. Disturbances in mineral and bone metabolism are prevalent in CKD and are an important cause of decreased quality of life, cardiovascular morbidity and mortality; these disturbances settle in earlier and have a more severe evolution in DM patients.
Authors and Affiliations
Iulia-Daniela Vladu, Daniela Cana, Cristina Vaduva, Corina Grauntanu, Sorin Zaharie, Raluca Dina, Ciprian Dina, Roxana Mustafa, Eugen Mota
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