COMPARISON OF HAEMODYNAMIC PROFILE AFTER SPINAL ANAESTHESIA IN PATIENTS ON REGULAR TREATMENT WITH CALCIUM CHANNEL BLOCKERS AND β BLOCKERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 34
Abstract
BACKGROUND Hypertensive patients develop wide swings in blood pressure intraoperatively, especially after spinal anaesthesia. Long term antihypertensive agents can modify this effect by controlling blood pressure. This study was undertaken to evaluate the haemodynamic effect in hypertensive patients on regular treatment with calcium channel blockers and beta-blockers who are undergoing elective surgery under spinal anaesthesia and compared with normotensives. AIMS To study the intraoperative changes of blood pressure and heart rate in patients on calcium channel blockers and beta-blockers undergoing surgery under spinal anaesthesia and to compare the data with normotensive patients. MATERIALS AND METHODS 90 patients were included in the study; 30 patients were normotensives (Group N) and 30 patients were hypertensives who were regularly on calcium channel blockers (Group C) and 30 patients on beta-blockers (Group B). Both the groups continued the drug on the day of surgery. The baseline blood pressure and heart rate were recorded. After spinal anaesthesia, the blood pressure and heart rate were noted at 2 min, 4 min, 6 min, 8 min, 10 min, 15 min and thereafter with 5 minutes interval till the end of the procedure. STATISTICAL ANALYSIS Baseline data was analysed using descriptive statistics. Intragroup variation in parameters analysed by one way ANOVA and within the different time intervals by post-hoc test. Intergroup comparison by unpaired ‘T’ test. P value <0.05 considered statistically significant. RESULTS The hypotension was evident in Group C compared to other groups, but bradycardia (heart rate <60) more seen in Group B and were statistically significant (P<0.001). The usage of rescue medication was more in study group and was statistically significant (P<0.002). CONCLUSION Incidence of hypotension was more with patients on calcium channel blockers and required vasopressors and fluids, but incidence of bradycardia was seen more in patients on beta blockers who needed atropine. Anaesthesiologists should anticipate and be adequately prepared for any untoward consequences.
Authors and Affiliations
Kavyashree , Muralidhara Patel, Girish , Ravishankar
Keywords
Related Articles
- EP ID EP101737
- DOI 10.14260/jemds/2016/455
- Views 138
- Downloads 0
TOTAL INTRAVENOUS ANAESTHESIA USING PROPOFOL AND KETAMINE COMBINATION VERSUS PROPOFOL AND FENTANYL COMBINATION IN PATIENTS UNDERGOING BRONCHOALVEOLAR LAVAGE
BACKGROUND Flexible bronchoscopy being an invasive procedure can induce cough, pain etc., thus requiring deep sedation or anaesthesia to offset these adverse effects. Aim- To compare the combination of Propofol with Keta...
STUDY OF HORMONE RECEPTOR STATUS IN CARCINOMA BREAST
BACKGROUND Breast cancer is the most common cancer in women. The mortality due to this disease is decreasing in western countries, because of early detection and effective systemic adjuvant therapy. In India incidence is...
ULTRASOUND AS A TOOL FOR ENDOTRACHEAL TUBE CONFIRMATION IN PATIENTS WITH OR WITHOUT DIFFICULT AIRWAY UNDERGOING ELECTIVE SURGERY
BACKGROUND Aims- Ultrasound is underutilised but effective tool for airway evaluation and management in emergency and elective conditions. In this study, primary aim was to compare the confirmation time for endotracheal...
ANGIOSARCOMA OF BONE- A RARE ENTITY
Angiosarcoma is rare and constitutes < 1% of all malignant bone tumours. A seventy two year male presented with pain and soft tissue swelling around L4 vertebral body compressing nerve root. An uncomplicated...
COMPARISON OF WHO AND RECIST RESPONSE CRITERIA IN LOCALLY ADVANCED BREAST CANCERA DESCRIPTIVE STUDY
BACKGROUND The current trend in management of Locally Advanced Breast Cancer (LABC) has changed from radical surgery to multimodality approach involving surgery, radiotherapy and chemotherapy. The efficacy of anticancer...