EXPERIENCE OF MANAGEMENT OF PHYLLODES TUMOR OF BREAST AT A TERTIARY CARE HOSPITAL: A PROSPECTIVE STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 15
Abstract
BACKGROUND Phyllodes tumors of the breast are a rare fibroepithelial lesions, which is locally aggressive neoplasm. The aim of the study was to report our experience at ESIC MC PGIMSR Hospital (Rajajinagar, Bengaluru) acquired during period of 3 years. METHODS It was a prospective observational study, which included documentation of clinical presentation, pre-operative workup, surgical treatment, complications, histopathological examination and the outcome in a series of 52 cases diagnosed as phyllodes tumor from January 2013 to December 2015. RESULTS The analysis of this series showed that mean time of onset was 12 months [6 – 18 months], the chief complaint was lump in the breast in all the patients; tumor size ranged between 4.5 – 22.5cm (mean: 13.5cm); the right breast was affected in 31 cases, surgical treatment was used in all cases which included 44 cases who underwent wide local excision and 8 cases simple mastectomy; the tumor was classified based on histopathological examination as benign in 44 cases (85%), borderline in 2 cases (4%) and malignant in 6 cases (11%); all the patients were followed up, the rate of recurrence was 10%. None of the patient had distant metastasis and no deaths were reported during the study period. CONCLUSIONS Phyllodes tumors of the breast clinically resemble fibroadenoma and have an unpredictable outcome, thus a wide local excision, with an adequate margin of normal breast tissue is the preferred initial therapy
Authors and Affiliations
Bharath , Lakkanna , Satyanarayan , Usharani , Preetham , Shankarappa , Arun S. L, Sagar
Keywords
Related Articles
- EP ID EP128508
- DOI 10.14260/jemds/2016/163
- Views 90
- Downloads 0
CLINICO-BIOCHEMICAL STUDY OF PATIENTS WITH THYROID SWELLING AT A TERTIARY CARE CENTRE
BACKGROUND Thyroid is one of the largest endocrine organs, associated with cell differentiation, development and metabolic homeostasis in body. Thyroid swelling is a common thyroid disorder. This study was intended to fi...
STUDY OF HYPONATREMIA IN PAEDIATRIC PATIENTS WITH ACUTE LOWER RESPIRATORY TRACT INFECTION
BACKGROUND Hyponatremia is one of the most common electrolyte abnormalities seen in paediatric intensive care unit. Common conditions associated with hyponatremia are pneumonia, acute meningitis, and Kawasaki disease. We...
TERATOCARCINOSARCOMA OF THE NASAL AND MAXILLARY SINUS MASS- A RARE CASE
PRESENTATION OF CASE A 42-yr. old man presented with chief complaints of nasal blockage, nasal bleeding and later on pain in the eyes and headache and progress to nasal mass within period of 3 months. Routine haematologi...
PROSPECTIVE STUDY ON COMPARISON OF INTRAOPERATIVE FROZEN SECTION AND CYTOLOGICAL TECHNIQUES AS DIAGNOSTIC MODALITIES OF OVARIAN MASS LESIONS
BACKGROUND Frozen section and cytology in gynaecological pathology have received less attention till date. This research focusses on indications and limitations of per-operative diagnostic techniques in pathology. Ovaria...
UTERINE LEIOMYOMATOSIS WITH OSSIFICATION: CASE REPORT OF A RARE ENTITY
Leiomyomas are benign and common smooth muscle neoplasms, occurring commonly in uterus. A spectrum of histological variants and secondary changes may accompany this entity; however ossification in a leiomyoma is a ra...