HYPOXIC ISCHAEMIC ENCEPHALOPATHY: ASSESSMENT OF SEVERITY BY MR IMAGING
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 63
Abstract
CONTEXT Perinatal asphyxia happens in 2 to 10 per 1000 newborns that are born at term, and more for those that are born prematurely and making one of the leading cause of death worldwide. AIM To study the pattern of involvement of brain in HIE influenced by nature of insult and to assess the severity of brain injury by MR imaging and correlate with clinical staging (Sarnat criteria). METHODOLOGY 43 cases with history of perinatal asphyxia were included in this study by applying the inclusion criteria and exclusion criteria. Signal changes in T1 and T2 weighted images and diffusion weighted were assessed and recorded. RESULTS AND INTERPRETATIONS After MR imaging, most of the Sarnat Stage I and II patients were mild and stage III patients were severe. Of the all clinically diagnosed having HIE, 25.6% cases were normal. Patients with clinically mild hypotension >1/2 (54.2%) of them were found to be normal after imaging. Patients with clinically moderate hypotension, 20% were normal at MRI; and >1/2 (52%) of them showed only mild changes and 12% showed severe involvement. Term babies with mild encephalopathy shows more involvement of periventricular white matter than subcortical white matter. Clinically severe encephalopathy correlates with abnormal basal ganglia – thalamic lesions in term babies and germinal matrix haemorrhage in preterm babies. Clinically moderate encephalopathy correlates with signal changes in posterior limb of internal capsule and perirolandic white matter. Prematurity increases the susceptibility of brain to changes caused by hypoxia. No significant association noted between sex and birth weight with abnormal MR imaging findings. The low Apgar score shows significant association with severity of brain involvement. Seizure and its onset also appears to be a deciding parameter in severity of brain injury
Authors and Affiliations
Sajitha , Vadakooth Rajendran, Jineesh , Juvaina , Saanida
Keywords
Related Articles
- EP ID EP128697
- DOI 10.14260/jemds/2016/1019
- Views 63
- Downloads 0
SPECTRUM OF PERFORATION PERITONITIS AT A TERTIARY CARE CENTRE IN PUNJAB
BACKGROUND Perforation peritonitis is the most common surgical emergency encountered by the surgeons all over the world. It requires an urgent surgical intervention and is a significant cause of morbidity and mortality....
MORPHOLOGICAL PATTERN OF BONE MARROW IN MULTIPLE MYELOMA- A DESCRIPTIVE STUDY
BACKGROUND Multiple myeloma is a bone marrow based plasma cell neoplasm that often presents with multifocal and disseminated involvement. Not surprisingly bone marrow examination is a key to its diagnosis along with labo...
A COMPARATIVE STUDY OF EFFICACY OF CENTCHROMAN AND EVENING PRIMROSE OIL IN TREATMENT OF BENIGN BREAST DISEASE
BACKGROUND Fibroadenomas are the most common breast lumps in women younger than 30 yrs. of age and the most common solid tumours in breast of women of all ages with a peak incidence at around 20 yrs. of age. Hormonal the...
A STUDY OF SPIROMETRIC LUNG FUNCTION TETS AND ITS CORRELATION WITH HIGH RESOLUTION COMPUTED TOMOGRAPHY IN PATIENTS OF RHEUMATOID ARTHRITIS
Rheumatoid arthritis is disease which usually starts as an insidious symmetrical polyarthritis often with non specific systemic symptoms. Pleuropulmonary involvement is a important cause of morbidity and mortal...
A COMPARATIVE EVALUATION OF ELECTRONIC FOETAL MONITORING VS INTERMITTENT AUSCULTATION AFTER AN INITIAL SCREENING ADMISSION TEST AND ITS IMPACT ON NEONATAL OUTCOME
BACKGROUND Continuous electronic foetal monitoring is presumably a superior method of screening for foetal hypoxia as it detects subtle changes in the foetal heart, which can be missed on auscultation. However, in develo...