Phytochemical analysis, antimicrobial, antioxidant activities and total phenols of Ferulago carduchorum in two vegetative stages (flower and fruit)
Journal Title: Pakistan Journal of Pharmaceutical Sciences - Year 2016, Vol 29, Issue 2
Abstract
Ferulago carduchorum (Apiaceae family) is an endemic plant of Iran. The crude extract and four fractions of aerial parts of F. carduchorum in two vegetative stages (flower and fruit) were studied for their total phenolic contents, antimicrobial and antioxidant activities using folin-ciocalteu assay, micro dilution method and DPPH assay, respectively. The results indicated that the best antioxidant activity was determined in flower crude extract (IC50=0.44mg/mL). The flower ethyl acetate fraction (FLE) showed better antimicrobial and antifungal activities than other fractions. So, FLE was selected for phytochemical investigations, resulting in isolation of a flavonoid (hesperetin). Hesperetin showed antimicrobial activity. The results showed that the antimicrobial and antioxidant effects during the flowering are obviously more than the fruit season.
Authors and Affiliations
Fereshteh Golfakhrabadi , Mohammad Reza Shams Ardekani , Soodabeh Saeidnia , Fatemeh Yousefbeyk , Hossein Jamalifar , Nasrin Ramezani , Tahmineh Akbarzadeh , Mahnaz Khanavi
Keywords
Related Articles
- EP ID EP117916
- DOI -
- Views 91
- Downloads 0
Preliminary antibacterial evaluation of the chemical compositions in Herba pogostemonis oil
In the present study, the antibacterial tests of herba pogostemonis oil were studied by using molecular- docking technology and antibacterial test in vitro. The 3 three-dimensional (3D) structures of the 5 compared...
Anti hyperalgesic potentials of Laggera aurita in Swiss Albino mice
The ethnomedical uses of Laggera aurita (LA), including its anti-nociceptive properties have been documented in literature. This study evaluated the anti-hyperalgesic effects of the methanolic extract of LA (MELA)...
Association study between 5-HT2A and NET gene polymorphisms and recurrent major depression disorder in Chinese han population
a functional NET T-182C polymorphism (rs2242446) in the promoter region, a synonymous polymorphisms G1287A in the exon 9(rs5569) and a functional serotonin 2A (5-HT2A) receptor (rs6311) genes in the promoter region...
Analysis on diagnostic value of esophageal electrophysiological examination for positive atropine test
To discuss the cause of positive atropine test and the possible reason for false positive atropine test, providing a certain aids for clinical diagnosis and treatment. Eighty patients, conducted atropine test due t...
Study of phenolic content and urease and alpha-amylase inhibitory activities of methanolic extract of Rumex acetosella roots and its sub-fractions in different solvents
The present study aimed to establish relationship between urease and alpha-amylase inhibitory activities on the one hand and on the other between anti-enzymatic activities and total phenolic contents of the methano...