PRONIOSOMES:- A NOVEL DRUG CARRIER FOR TRANSDERMAL DRUG DELIVERY
Journal Title: Int J of Pharm Rev& Res - Year 2016, Vol 6, Issue 1
Abstract
ABSTRACT The purpose of the current study was to investigate the feasibility of proniosomes as a novel drug carrier for Transdermal drug delivery. This article describes the proniosome- derived niosomes. Niosomes are non-ionic surfactant vesicles that can entrap a solute in a manner analogous to liposomes. Niosomes have been prepared from several classes of non- ionic surfactants. Niosomes may be unilamellar or multilamellar depending on the method used to prepare them. In recent years, niosomes have been extensively studied for their potential to serve as carrier for delivery of drugs, antigen, hormone and other bioactive agents. The basic aim in developing the delivery system is controlling the release of drugs from the carrier system, in order to achieve an extended uptake in the body. Proniosomes are water soluble carrier particles that are coated with surfactant and can be hydrated to form a niosomal dispersion immediately before use on brief agitation in hot aqueous media. This review presents an overview about proniosomes regarding their preparation, characterization and transport of various drugs through skin. Key words: Niosomes, Proniosomes, Transdermal drug delivery, Vesicles, Non-ionic.
Authors and Affiliations
Kuthadi Priyanka* and Aseema Nasreen
Keywords
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