Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India
Journal Title: International Journal of Medical Science and Public Health - Year 2016, Vol 5, Issue 4
Abstract
Background: Hepatitis C is endemic in most parts of the world. It is a blood borne infection, which has a significant impact in treatment and outcome of renal failure patients undergoing dialysis. Objective: To determine the seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis in a tertiary care hospital. Materials and Methods: This study was carried out retrospectively on patients undergoing hemodialysis whose samples were received for Hepatitis C screening in the Department of Microbiology, BJ Medical College, Ahmedabad, Gujarat, India. A total of 910 patients were included in the study conducted over a period of 12 months. Screening for anti-hepatitis C virus (HCV) antibodies was done by a third-generation enzyme-linked immunosorbent assay and their epidemiological data were analyzed. Result: Of the 910 patients screened for anti-HCV antibodies, 25 patients were found to be positive for Hepatitis C. The overall seroprevalence of hepatitis C among dialysis patients was 2.7%. The HCV positive rates were more among the males and highest in the age group of 30–60 years. Only 44% seropositive patient had raised alanine transaminase level. Conclusion: Regular screening of hepatitis C patients is mandatory as it has a detrimental effect contributing to morbidity and mortality. Strict adherence to infection control practices should be prioritized in the health-care settings to reduce the burden of disease among the high-risk groups.
Authors and Affiliations
Geetha Priyadharsini Subramanian, Mahendra M Vegad, Minesh G Vadsmiya, Sweta M Murawala, Falguni V Patel
Keywords
Related Articles
- EP ID EP128260
- DOI 10.5455/ijmsph.2016.22072015109
- Views 85
- Downloads 0
Effect of immunization counseling skills training in third-year medical students
Background: In India, the coverage of immunization is low due to low morale and lack of information. Parents who refuse to vaccinate their children or do not comply with the immunization schedule of their children ma...
Perceptions and outlook towards HIV/AIDS among reproductive age group of urban slum population
Background: Acquired Immunodeficiency Disease Syndrome (AIDS) has evolved into a pandemic affecting millions of people worldwide. The global HIV/AIDS epidemic has had a major detrimental impact on high risk group...
A psychotropic drug use study among depression patients attending private psychiatric practitioners of Dehradun, Uttarakhand
Background: Drug use studies are beneficial in clinical practice for rational prescribing of drugs and helpful for minimizing the medication errors. Aims and Objectives: The present study investigates the prescrib...
Obstructive sleep apnea: an experience
Background: Obstructive sleep apnea (OSA) is a common disorder of repetitive pharyngeal collapse during sleep. It is more common among middle-aged adults. Obesity leads to and intensifies OSA. Epidemiologic studie...
Comparative study of lipid profile between episodic migraineurs and healthy volunteers
Background: The lipid profile of migraineurs showed atherogenic condition. Cardiovascular and cerebrovascular events were found to be frequent and appeared one decade earlier in migraine patients compared with the ge...