STUDY OF DENGUE INFECTION IN RURAL RAJASTHAN
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2015, Vol 4, Issue 39
Abstract
[b]BACKGROUND[/b]: Dengue has a wide spectrum of clinical presentation in paediatric population, often with unpredictable evolution and outcome. AIMS: To record the clinical, laboratory & radiological profile of dengue in hospitalized children and to enlist the predictive markers of severity in patients with severe dengue. [b]SETTINGS AND DESIGN[/b]: This observational, prospective hospital- based study was conducted in 100 admitted children aged 9 months - 18 years with clinical and laboratory confirmation of dengue illness. [b]METHODS[/b]: All the 100 subjects included in this study were classified in three groups- Dengue without warning signs (D) Dengue with warning signs (DW) and severe dengue (SD) on the basis of 2009 WHO Guidelines followed by laboratory and radiological evaluation.[b] STATISTICAL ANALYSIS:[/b] involved summarizing the continuous variables as mean and standard deviation, while nominal/categorical variables were expressed as percentages. Chi square test was used for analysis of nominal/categorical variables. Stepwise Multivariate Logistict Regression analysis was employed to determine the predictors for severe dengue. [b]RESULTS[/b]: 52 patients had dengue without warning signs (D), 40 patients had dengue with warning signs (DW) and 8 patients had severe dengue (SD). Fever was present in 52(100%) cases, myalgia in 31(59.62%) cases followed by hepatomegaly in 20(38.46%) cases was seen in D group while in DW group fever in 40(100%), vomiting in 34(85%), pain abdomen in 33(82.50%) and hepatomegaly in 11(52.50%) cases was seen. In SD group, fever, myalgia, vomiting, pain abdomen, rash, positive Hess test, pallor, hepatomegaly was observed in all the cases (P value <0.001.). Presence of commonly described features like rash (13%), positive Hess test (8%) and bleeding manifestations (7%) in few cases only was a prominent feature observed in the study subjects. Raised SGOT/ SGPT levels, prolonged PT and APTT, hypoalbuminemia, pleural effusion in skiagrams of chest and increased gall bladder wall thickness (GBWT)>3mm in USG scan was significantly associated with SD. Among several predictors, GBWT was observed to be strongly correlating with severity of dengue infection. [b]CONCLUSION[/b]: Dengue is becoming more prevalent in India especially in rural areas. As it may have a non-specific presentation, it should be suspected in every case of febrile illness in post-monsoon season.
Authors and Affiliations
Manisha Rathi, Rupesh Masand, Alok Purohit
Keywords
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- EP ID EP111932
- DOI 10.14260/jemds/2015/993
- Views 101
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