Nerve conduction studies in cases with long-term unintentional exposure to pesticide spraying
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 2
Abstract
Background: Farm workers experience many work-related hazards, including exposure to organophosphorus (OP) compounds during the process of pesticide spraying during their crop season. The recurrent unintentional exposure to OP compounds may lead to motor and sensory nerve neuropathies and also have some delayed neurological sequels. Aims and Objectives: The aims of this study were (1) to find out the toxic effects of OP compound on motor nerve conduction velocity (MNCV) and (2) to compare the MNCV, in selected peripheral nerve (median nerve) of affected population with the normal population. Materials and Methods: A cross-sectional analytical study was conducted by recruiting 60 individuals matched with height, weight, and occupation matched (control group 30 and study group 30). Participants were selected randomly from the outpatient Department of Medical College Hospital with age group between 20 and 40 years, and both sexes were included. The MNCVs were recorded using multichannel polyrite machine. Results: MNCVs were evaluated on median nerves of both the sides. MNCV was recorded on distal stimulation. Our findings show that the motor abnormalities nerve velocities in case of exposed population were significantly less as compared to the controls in tested median nerve. This indicates the presence of abnormalities such as neuropathy in these patients. Conclusion: There was an evidence of peripheral neuropathy to some extent in peripheral nerves as evident by slow MNCVs in median nerve of those farmers who were exposed to the OP pesticide spraying in the farms and its consequent absorption through skin, inhalation, or ingestion as compared to the normal individuals.
Authors and Affiliations
Sakshi Gawande, Shivaji Chalak, Ashish Banginwar, Kiran Avachar, Jagdish Powar, Prafulla Chandak
Keywords
Related Articles
- EP ID EP451652
- DOI 10.5455/njppp.2018.8.0831918082017
- Views 75
- Downloads 0
Patient-based integrated teaching program with the inclusion of psychomotor and affective domains
Background: Integrated teaching program (ITP) is a solution to the compartmentalized teaching of fragmented and passive learning. However, ITP is conducted mainly in the form of lectures, whereas in our study, we have in...
Effect of age on cardiac output after coronary angioplasty in patients of acute myocardial infarction
Background: Although most of the acute coronary syndrome (ACS) patients are elderly, less data available on the effect of age on outcome after percutaneous coronary interventions (PCI) and major adverse cardiovascular ev...
Sleep duration among undergraduate medical and science degree college students: A comparative study
Background: There is an increasing incidence of sleep deprivation in all ages, with college students being specially affected. Medical students are even more susceptible to it, which may affect health-care system. Aims a...
Nerve muscle physiology changes with yoga in professional computer users
Background: Nerve muscle dysfunction is a common cause of occupational injuries collectively called as repetitive stress injury or musculoskeletal diseases adversely affecting the patients socially and economically. Yoga...
A study on antidepressant-like effect of dihydroxy flavones in mice and their mechanisms involved
Background: In the treatment of depression, drugs with a quick onset of action and high margin of safety are intensely being searched. Previous studies indicate flavonoids as a potential source for such drugs. Hence, in...