Neuropharmacological Consequences of Variant Drugs
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2017, Vol 6, Issue 11
Abstract
Neuropharmacological effects deals with the influence of drugs on nervous system which harvest the changes in mood, behavioral action of an individual. The drugs are characterized by the chemical substances that communicate with the neurons which have different impacts on nervous system. It may either conducts the abusive or pleasure response which depends on the neural chemicals activity and concerns with the licit and illicit drugs. The elucidation of drugs via LC/MS shows its exertion on the brain components. The computational model helps in the identifcation of signaling pathways that trigger or inhibit the neurotransmitters. The licit drugs have indisputable responses on CNS. It imparts neuroprotection by either stimulating or inhibiting the receptor, by down regulation yield antinociceptors. However, the illicit drugs have negative acknowledgment on the body as in nicotine the fewer amounts provides benefts but in higher amount mimics the activity of brain receptors and replaces it. Many other drugs induce neurodegenerative disorders. Due to advances in feld of neuropharmacology innumerable drugs are available for feasible treatment. The main objective of this review is neuropharmacological consequences in correlation to licit and illicit drugs that what type of responses generated by using these drugs, the neurodegenerative disorders, and their restoration via current treatment.
Authors and Affiliations
Mahnoor Amjad Butt| Department of Biotechnology, University of Gujrat, Sialkot Sub Campus, Sialkot, Punjab, Pakistan, Corresponding e-mail: mahnooramjad0786@gmail.com, Pervez Anwar| Department of Biochemistry and Molecular Biology, University of Gujrat, Sialkot Sub Campus, Sialkot, Punjab, Pakistan, Pervez.anwer@uogsialkot.edu.pk, Zeshan Ali| Department of Biotechnology, University of Gujrat, Sialkot Sub Campus, Sialkot, Punjab, Pakistan, Zainab Razaq| Department of Biotechnology, University of Gujrat, Sialkot Sub Campus, Sialkot, Punjab, Pakistan, Ali Numan| Department of Biotechnology, University of Gujrat, Sialkot Sub Campus, Sialkot, Punjab, Pakistan, Kinza Tahir| Department of Biotechnology, University of Gujrat, Sialkot Sub Campus, Sialkot, Punjab, Pakistan, Iqra Awan| Department of Biotechnology, University of Gujrat, Sialkot Sub Campus, Sialkot, Punjab, Pakistan, Momina Abid| Department of Biotechnology, University of Gujrat, Sialkot Sub Campus, Sialkot, Punjab, Pakistan, Ahsan Khan| Department of Biotechnology, University of Gujrat, Sialkot Sub Campus, Sialkot, Punjab, Pakistan, Sibgha-Tur-Rehman| Department of Biotechnology, University of Gujrat, Sialkot Sub Campus, Sialkot, Punjab, Pakistan, Sania Ibrar| Department of Biotechnology, University of Gujrat, Sialkot Sub Campus, Sialkot, Punjab, Pakistan
Keywords
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