Neuropharmacological effects of Albizzia Chinensis extract
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2018, Vol 5, Issue 3
Abstract
Introduction To know the Neuropharmacological effects of Albizzia chinensis extract in rats and miceMaterials and Methods The test compound was evaluated experimentally for its neuropharmacological activities in rats and mice Blind neuropharmacological screening potentiation of barbiturate hypnosis stimulation of the central nervous system maximal electroshock and pentylenetetrazol induced convulsions analgesic activity were studiedResults The compound potentiated pentobarbital hypnosis reduced spontaneous motor activity antagonized amphetamine induced hyperactivity blocked the conditioned avoidance response without affecting the unconditioned response and showed analgesic activity by the tailflick method but not in hot plate model in the experimental animalsConclusion The compound is similar to chlorpromazine and morphine Keyword Saponin Central nervous system Animals
Authors and Affiliations
Dinesh Kansal, Naresh Gupta
Keywords
Related Articles
- EP ID EP478559
- DOI 10.18231/2393-9087.2018.0028
- Views 108
- Downloads 0
A Cross-Sectional study of Drug Prescription Pattern in Urticaria patients attending Dermatology & Venereology Department in a Rural Tertiary Care Teaching Hospital
Background: Urticaria is a very common skin condition characterized by recurrent, pruritic (itchy), pink-to-red edematous (swollen) lesions that often have pale centers (wheals). Histamine is the main mediator of urticar...
Enhancing Communication skills by Role Plays in Endocrine Pharmacology: Students Perspective
Communication skill is one of the six required competencies by the Accreditation Council for Graduate Medical Education (ACGME). They can have a better outcome if practiced than just preached. Role plays are widely used...
Formulation and evaluation of orodispersible tablet containing piroxicam by sublimation method
The most preferred route of administration is oral administration of any dosage form because of its self-medication, exact dose of drug and easily administration but difficulty in swallowing in geriatric patients is one...
Chicken ileum: a better option for conducting isolated tissue experiments and bioassay
In vivo method of animal testing is the use of non-human animals in experiments. Mice, rats, rabbits, guinea pigs, hamsters and non-human primates are widely used as laboratory animals. In vitro cell culture technique an...
Antidepressant activity of ciprofloxacin and levofloxacin by using tail suspension test in Swiss albino mice on chronic administration
Introduction Depression is evidenced by decreased mood and reduced activity that can affect person39s thoughts behavior feelings and also sense of wellbeing in the society Use of long term antidepressant agent pose a sig...