New Spectrophotometric Determination of Esomeprazole in Bulk And Pharmaceutical Dosage Form Using Tropaeoline-OO
Journal Title: IOSR Journal of Applied Chemistry (IOSR-JAC) - Year 2018, Vol 11, Issue 6
Abstract
The new, selective and sensitive visible spectrophotometric method has been developed for the estimation of Esomeprazole in bulk and in pharmaceutical preparations. This method is based on the reaction with tropaeoline-00 dye under acidic condition with a λmax 410nm. Beer’s law is obeyed in the concentration range of 50-250µg/ml for both the methods. The method was extended to pharmaceutical formulations and there was no interference form in any common pharmaceutical excipients and diluents. The result of analysis has been validated statistically and by recovery studies.
Authors and Affiliations
M. M. V. YOGANANDASWAMY, Dr. A. J. PRATAPA REDDY
Keywords
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- EP ID EP414081
- DOI 10.9790/5736-1106015962.
- Views 173
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