Nutritional status and physical activity of childhood leukemia survivors

Journal Title: Paediatrica Indonesiana - Year 2014, Vol 54, Issue 2

Abstract

Background Acute lymphoblastic leukemia (ALL), the mostcommon malignancy of childhood, has an overall cure rate ofapproximately 80%. Long-term survivors of childhood ALL areat increased risk for obesity and physical inactivity that may leadto the development of diabetes, dyslipidemia, metabolic syndrome,as well as cardiovascular dis eases, and related mortality in theyears following treatment.Objective To evaluate the physical activity and the propensityfor developing obesity longer term in ALL survivors.Methods This retrospective cohort study included all ALLsurvivors from Pantai Indah Kapuk (PIK) Hospital. We assessedtheir physical activity and nutritional status at the first time ofALL diagnosis an d at the time of interview.Results Subjects were 15 ALL survivors aged 7 to 24 years. Themedian fo llow up time was 6.4 years (range 3 to 10 years). Only2 out of 15 survivors were overweight and n one were obese.All survivors led a sedentary lifestyle. Most female subjectshad increased BMI, though most were not overweight/obese.Steroid therapy in the induction phase did not increase the riskof developing obesity in ALL survivors.Conclusion Lon g-term survivors of childh ood ALL do not meetphysical activity recommendations according to the CDC (Centersfor Disease Control). Howevei; steroid therapy do not seem tolead to overweight/obesity in ALL survivors.

Authors and Affiliations

Conny Tanjung, Johannes Lukito, Prima Meylani

Keywords

Related Articles

Nutritional status of soil-transmitted helminthiasis-infected and uninfected children

Background Soil-transmitted helminth (STH) infections remain a public health problem in developing countries. Their prevalence is particularly high in rural areas with people of low socioeconomic level. A single or mixed...

Comparison of SpO2/FiO2 and PaO2/FiO2 ratios as markers of acute lung injury

Background One of the diagnostic criteria for acute lung injury (ALI) is the PaO2/FiO2 (P/F) ratio. This measurement is obtained by blood gas analysis, which involves an invasive procedure (arterial blood draw). In order...

High sensitivity C-reactive protein, left ventricular mass, and systolic function in obese adolescents

Background Obesity has been associated with structural and functional cardiac muscle defects. High sensitivity C-reactive protein (hs-CRP) has been utilized as an independent predictor of future cardiovascular disease.Ob...

Predictors of mortality in children with lupus nephritis

Background Renal involvement during the clinical course ofsystemic lupus erythematosus (SLE) is generally considered to bethe most important factor influencing disease prognosis in termsof morbidity and mortality. Variou...

Mortality rates in pediatric septic shock

Background Septic shock remains a major cause of morbidity and mortality in children admitted to the intensive care unit. Recent investigations from developed countries have reported mortality rates of 20-30%. Few studie...

Download PDF file
  • EP ID EP458704
  • DOI 10.14238/pi54.2.2014.67-72
  • Views 77
  • Downloads 0

How To Cite

Conny Tanjung, Johannes Lukito, Prima Meylani (2014). Nutritional status and physical activity of childhood leukemia survivors. Paediatrica Indonesiana, 54(2), 67-72. https://www.europub.co.uk/articles/-A-458704