OCCURRENCE AND RESISTANCE PROFILE OF NONFERMENTATIVE GRAMNEGATIVE BACILLI IN A TERTIARY CARE HOSPITAL – A THERAPEUTIC CONCERN
Journal Title: IJSR-International Journal Of Scientific Research - Year 2018, Vol 7, Issue 8
Abstract
Aim: To isolate, identify and characterize the prevalence of non- fermenting gram negative bacteria (NFGNB) along with their antimicrobial resistance pattern among the patients attending a tertiary care Hospital in Meerut. Materials and Methods: The isolates of NFGNB obtained from various samples were identified by standard bacteriological technique and VITEK® 2 system (Biomerieux , France) . Antimicrobial susceptibility test was carried out to assess the resistance profile both by Kirby Baeur disk diffusion method and VITEK® 2 system (Biomerieux , France) . Result: A total of 16,296 clinical samples from the indoor and outdoor patients were processed in the bacteriology laboratory. Isolation rate of nonfermenters was 7.82% (1274/16296). Pseudomonas spp. was the predominant isolate (66.56%) followed by Acinetobacter spp. (27.16%). Other isolated non-fermenters were Burkholderia cepacia complex (BCC)(1.57%), Stenotrophomonas maltophila (0.86%), Sphingomona spaucimobilis (0.71%), Achromobacter xylosoxidans (0.16%), Ochrobactrum anthropic (0.16%). NFGNB are emerging as important opportunistic pathogens and are mostly resistant to commonly used Conclusion: antimicrobials. Therefore early diagnosis and initiation of appropriate antibiotic therapy would help in efficient management of patients and result in reduction of morbidity and mortality caused by these multi drug resistant organisms.
Authors and Affiliations
Kalpana Chauhan, Arjun Bisht, Ankita Gupta, Anita Pandey
Keywords
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