Ocular haemodynamic in patients with glaucoma measured by contrast-enhanced ultrasound
Journal Title: Eye Science (Yanke Xuebao) - Year 2021, Vol 36, Issue 6
Abstract
[Objective:] This study used Doppler imaging and contrast-enhanced ultrasound to measure ocular haemodynamic of patients with primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG), to investigate the association between the blood flow changes and glaucoma. [Methods:] Doppler imaging and contrast-enhanced ultrasound were performed on 16 PACG patients (20 eyes, PACG group), 8 POAG patients (10 eyes, POAG group) who were diagnosed in the Department of Ophthalmology, the Second Affiliated Hospital of Harbin Medical University from Dec. 2012 to Mar. 2014. The normal eyes from 10 persons were selected as control group. The flow velocity of ophthalmic artery, central retinal artery, and posterior ciliary artery were observed, including the peak systolic velocity, diastolic peak velocity, resistance index, and the arrival time and departure time of the ultrasound microbubbles (SonoVue). [Results:] Compared to control group, the arrival time of the ultrasound microbubbles (SonoVue) of ophthalmic artery of patients with POAG increased (P=0.035), and the departure time of ophthalmic artery of patients with PACG and POAG increased (P=0.010). Both peak systolic velocity and diastolic peak velocity of the ophthalmic artery and short posterior ciliary artery of patients with PACG and POAG and the central retinal artery of patients with POAG decreased (P=0.003). Meanwhile, the resistance index of ophthalmic artery of patients with PACG and POAG and the central retinal artery of patients with POAG were higher than those in the control group (P<0.001). [Conclusion:] The flow velocity of ocular vascular was worse than that of normal group respectively. This study provides a new technology for the diagnosis of glaucoma and the evaluation of the flow velocity of ocular vascular.
Authors and Affiliations
Linan HAN, Wulian SONG, Jingbo SUN, Huiping YUAN
Keywords
Related Articles
- EP ID EP763525
- DOI 10.3978/j.issn.1000-4432.2021.06.04
- Views 14
- Downloads 0
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