OCULAR MANIFESTATIONS OF MUCOCUTANEOUS DISORDERS: A PROSPECTIVE STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 32
Abstract
Dermatologic disorders usually have manifestations which involve the eyelids, conjunctiva, and cornea. The ocular complications may often be the most devastating outcome for survivors of the acute reaction. The key to success to minimize possibility of visual impairment is the prevention of complications. OBJECTIVES: This study highlights the ocular manifestations of various mucocutaneous disorders. MATERIALS AND METHODS: A prospective study was conducted in the Department of Ophthalmology in a medical college hospital, over a period of 1 year, on patients presenting with mucocutaneous syndromes who were referred from the Departments of Dermatology and Medicine. Patients with co-morbid diseases like diabetes and hypertension wherein ocular involvement is likely were excluded from the study. RESULTS: In this study, 103 patients with mucocutaneous disorders were examined, of which 65 (63.1%) had ocular involvement. Majority of the patients belonged to the 21-30 years age group; with a male preponderance. The most common mucocutaneous syndrome in this study was herpes (37%), followed by leprosy (27%). Ocular involvement was seen in 69% patients with herpes and 79% patients with leprosy. In this study, periorbital vesicles was the most common ocular manifestation in herpes (20%), followed by blepharitis, conjunctivitis, corneal epithelial defect and keratitis; however, in leprosy, madarosis (16%) was the commonest ocular lesion. Economic blindness (visual acuity <6/60) was seen in 6 cases, and visual handicap (visual acuity <6/18) in 20 cases. The most common cause of visual impairment was due to corneal implications. Over the course of next three months, 19 patients (25%) developed various ocular complications like dry eye (10%), corneal scar (5%), corneal vascularisation (3%), trichiasis (3%), symblepharon (8%), and ankyloblepharon (15%). CONCLUSION: Careful ophthalmic examinations during the early period of the skin reaction and early detection of complications like trichiasis, epithelial surface disease, and secondary infection can improve the outcome.
Authors and Affiliations
Soumya Sharat, Nagaraja K. S.
CLINICAL AND ULTRASONOGRAPHIC PREDICTORS OF FOETAL MACROSOMIA
BACKGROUND Foetal macrosomia is defined as foetal growth above the 90th percentile for a given gestational age or as foetal weight >4000 gms. In India, a baby weighing more than 3.25 kg would be greater than the 90th per...
MODALITIES OF MANAGEMENT OF VERNAL KERATOCONJUNCTIVITIS
BACKGROUND: Ocular allergy is a common disorder which can be debilitating for patients and, at times, challenging for physicians to diagnose and treat. Allergic disease affects 30–50% of the population. Vernal kerato con...
A RARE CASE OF ALL PRESENTING WITH UNILATERAL TONSILLAR ENLARGEMENT- A CASE REPORT
Acute Lymphoblastic leukemia (ALL) is more common in children and least in adults. About 6,000 people are diagnosed with ALL each year. Children account for two-thirds of these cases. ALL represents about 15% of all mali...
A STUDY TO EVALUATE OUTCOME OF IDIOPATHIC CLUBFOOT MANAGED BY PONSETI TECHNIQUE
BACKGROUND Club foot is the most common congenital disorder in orthopaedics. Over the years, many different forms of treatment ranging from gentle manipulation and strapping, serial plaster corrections, forcible manipula...
CLINICAL STUDY OF EARLY BREAST CARCINOMA
Carcinoma of the breast is one of the commonest cancers occurring in female and accounts for 1/3rd of all the malignant diseases occurring in them. It is mainly a disease of the developed countries and accounts for 1,00,...