Oligonol Supplementation Decreases Cardiometabolic Risk Factors, and the Prevalence of Metabolic Syndrome in a Sample of Overweight and Obese Saudi Females
Journal Title: Annual Research & Review in Biology - Year 2017, Vol 16, Issue 2
Abstract
Aims: Cardiovascular diseases (CVDs) are the primary cause of morbidity and mortality worldwide, with metabolic syndrome (MS) increasing their risk. We aimed to investigate the effects of oligonol on cardiometabolic risk factors in healthy overweight and obese Saudi females. Study Design: A double blind case/control design. Place and Duration of Study: The study was carried out during December 2015 to June 2016 in the Food, Nutrition and life style research unit, King Fahd Medical Research Centre. Subjects and Methods: A double blind case/control design was employed. 60 young, apparently healthy overweight and obese females were enrolled, and divided randomly into two groups to take either Oligonol or placebo for 12 weeks without dietary or lifestyle restrictions. Weight, height, waist circumference (WC), and blood pressure were measured and fasting blood samples taken before, and after supplement. Glucose, lipid profile, Apolipoprotein B, Gamma glutamyl transferase (GGT), and highly sensitive C-reactive protein (hs-CRP) were measured, and Atherogenic index of plasma (AIP) calculated in all blood samples. Obtained data was used to diagnose MS. Results: 25 subjects in placebo group and 22 in Oligonol group completed the study. No adverse effects were noted. Oligonol improved mean triglycerides, AIP, and hs-CRP, and decreased the number of subjects with high triglycerides, diastolic blood pressure, and WC, hence MS. Conclusion: Oligonol appears to decrease the risk of CVD in obese and overweight Saudi females by controlling or decreasing components of the metabolic syndrome, hs-CRP, and AIP.
Authors and Affiliations
Suhad M. Bahijri, Anwar Borai, Zuhier Awan, Ghada Ajabnoor, Gehan A. Hegazy, Lubna Alsheikh
Germination Characteristics of Parinari curatellifolia Planch. Ex Benth, Vitex doniana Sweet and Zanthoxylum zanthoxyloides (Lam) Watermann Seeds
Germination characteristics studies of seeds of three local species in Burkina Faso namely Parinari curatellifolia, Vitex doniana and Zanthoxylum zanthoxyloides have been carried out. The aim of this study was to carry o...
Physiological Features of Hemostasis in Newborn Calves Receiving Ferroglukin, Fosprenil and Hamavit, for Iron Deficiency
Newborn calves still often suffer from iron deficiency. This state damages their growth and development - to some extent, due to the development of pathological changes in hemostasis. Thereby, both veterinary science and...
A Quantum Mechanical Aspect of Enzyme Action: Enzymes as Information Driven Quantal Measurement Engines
In this introductory paper we overview existing approaches to enzyme – catalysed reactions. From the Michaelis – Menten kinetics to quantum scatterings several models are considered. We try to introduce our ”information...
Threats to Red Junglefowl (Gallus gallus murghi) in Deva Vatala National Park, District Bhimber, Azad Jammu and Kashmir, Pakistan
Aim: The aim of this study was to document threats to Red Junglefowl (Gallus gallus murghi). Place and Duration of Study: This study was conducted in Deva Vatala National Park, Bhimber Azad Jammu and Kashmir, Pakistan fr...
Concentration of Selected Heavy Metals in Sediments and Liver of Wild African Catfish (Clarias gariepinus) in Lake Kanyaboli, Kenya
It is evident that high heavy metal concentrations in sediments are eventually magnified along the aquatic lives like fish hence affecting human health. The present study therefore sought to determine the concentration o...