Outcome Analysis of Multi-Drug Resistant Tuberculosis Cases Treated by Individualized Regimens
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 3
Abstract
Multi-drug and extensively drug resistant tuberculosis (M/XDR-TB) has been an area of growing concern among clinicians, epidemiologists, and public health workers worldwide. This study was conducted with objective to assess the clinical, radiological, conversion rate as well as the association with each other in Multi-Drug Resistant Tuberculosis (MDR-TB). This hospital based analytical type of observational study was conducted in the department of Respiratory Medicine, JLN Medical College Ajmer, on the 244 Multidrug Resistant Pulmonary Tuberculosis patients at PMDT site were included who were consecutively enrolled for category IV regimen during period, 1st January to 30th September 2012 . They (N=103) were followed up for 24 months clinically, and bacteriological by sputum smear, culture and Drug Susceptibility Testing (DST) at regular intervals. The data were analyzed by chi square test. Out of 244 patients, 74.6% patients were in the reproductive and economically productive age group of 16 - 45 years. According to radiological outcome, 66.9% evidence of radiological improvement, whereas 24 (23.3%) patients had radiological deterioration, while in 10 (9.7%) patients radiological picture was stationary. statistically highly significant association between clinical symptoms, radiological and conversion among follow up patients was observed(p value < 0.001). Sputum smear and culture conversion are very well associated with clinical and radiological improvement. Category IV regimen of DOTS-Plus under RNTCP program in MDR-TB patients produced significant improvement in body weight, bacteriological, and radiological examination. Keywords: clinical symptoms, radiological, conversion, MDR patients.
Authors and Affiliations
Dr. Pradeep Pachar, Dr. Vikas Kumar Mishra, Dr. Rajveer Kuldeep, Dr. Neeraj Gour, Dr. Prerna Gupta, Dr. Rakesh C. Gupta, Dr. Paharam Adhikari
Keywords
Related Articles
- EP ID EP371153
- DOI -
- Views 73
- Downloads 0
Study of Effects and Complications of Hypertonic Saline in Cases of Hyponatremia
In case of hyponatremia when amount of sodium in fluids outside cells drops, water moves into cells to balance the levels. This causes swelling of cells. Although most cells can handle this swelling, brain cells cannot,...
Assessment of Over the Counter Topical Steroid Use amongthe Nursing Students in Mandya District
Topical corticosteroids (TCs) are the most commonly used therapeutic formulations by dermatologist and also widely misused cream by all in routine medical practice. Many adverse reactions have been described with topical...
Knowledge and Preventive Practices Regarding Dengue among Dengue Fever Cases Admitted at Tertiary Care Hospital, Rajkot, Gujarat, 2014
Abstract: Dengue is the most common disease among all the arthropod-borne viral diseases. Due to remarkable changes in the epidemiology of dengue, currently dengue ranks the most important mosquito-borne viral disease in...
Association of Otorhinolaryngological Trauma with Head and Neck Injury – An Epidemiological Study
Abstract: The Ear, Throat and face region is the area in the body that is commonly involved in head and neck injury. Trauma to this region is often associated with mortality and morbidity and varying degree of physical a...
Factors Affecting Fertility among Saudi Women
Abstract: The aim of this study is to assess fertility determinants among Saudi women. A cross sectional descriptive study design was used. All data was collected through distribution via online questionnaire (twitter, f...