Outcome of Different Therapeutic Interventions in Mild COVID-19 Infection
Journal Title: Journal of Clinical Immunology & Microbiology - Year 2021, Vol 2, Issue 2
Abstract
Background: Coronavirus disease 2019 (COVID-19) case and the death toll has reached milestones of over 12,28,22,505 and 27,09,041 respectively worldwide as of 22nd March 2021. Treatment regimens are cropping up daily and adding up to the dilemma of the treating physicians. Aims: This present study aimed to see the Clinical Response of Well-Being (CRWB) reporting time in mild COVID-19 infected patients after their treatment initiation in four different treatment arms. Methods: A total of 56 patients meeting the case definition of mild COVID-19 infection were included after the retrospective screening of the investigators’ electronic database. Patients were divided into four groups - Hydroxychloroquine (HCQ) taking group, patients on the combination of Doxycycline (DOX) + Ivermectin (IVR), Azithromycin (AZ) taking group and symptomatic treatment receiving group. Results: There was no difference in CRWB between the four groups (p-value 0.846). The group on symptomatic management arm showed significant correlation between CRP (p-value 0.01), LDH (p-value 0.001), and age (p-value 0.035) with CRWB. Significant correlation was also seen between blood levels of CRP (p-value 0.03), LDH (p-value 0.001) and D-dimer (p-value 0.04) with CRWB in the IVR+DOX group. Conclusion: No specific drug treatment is required to treat mild COVID-19 infection other than symptomatic management in patients with a low risk of progression.
Authors and Affiliations
Sayak Roy*, Shambo Samrat Samajdar, Santanu K Tripathi, Shatavisa Mukherjee, Kingshuk Bhattacharjee
Keywords
Related Articles
- EP ID EP699100
- DOI http://dx.doi.org/10.46889/JCIM.2021.2203
- Views 127
- Downloads 0
Lyme Disease-An Emerging Metazoonosis of Public Health Concern
Recent decades witnessed the emergence of several zoonotic diseases, such as bird flu, Ebola disease, Nipah virus disease, severe acute respiratory syndrome, swine flu, COVID-19 and others [1]. The emergence of these z...
Association between Non-Right-Handedness and Multiple Sclerosis (MS)
Background: Only two studies have examined the relationship between handedness and Multiple Sclerosis (MS). Objective: To extend previous work examining any relationships between MS and handedness. Methods: Using a...
Candidemia: A Hospital Based Study in Haematological Patients in Adult Population of Northern India
Background: Candidemia has become a common cause of fungal infection in bloodstream infection throughout the world. In hematological malignancies, patients have high rate of morbidity and mortality due to Candidemia. Obj...
A Narrative Review on Argentine Hemorrhagic Fever: Junin Virus (JUNV)
Epidemic cases of Argentine hemorrhagic fever (also known as AHF) have been associated with the Junin virus, also known as JUNV, ever since the 1950s. The JUNV arenavirus is endemic to the countries of the New World. In...
Macrophage Responses Against Acellularized Dermal Matrix from Human Versus Porcine Predicts the In-vivo Fibrosis
Background: Due to the possible difference in the manufacturer’s processes, in-vitro and in-vivo tests might be beneficial for the selection of an Acellularized Dermal Matrix (ADM). Methods: ADMs from human and porcin...