PATTERN OF EXTRA-PULMONARY TUBERCULOSIS IN PATIENTS WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION, AT A TERTIARY CARE CENTRE IN EASTERN INDIA
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2015, Vol 4, Issue 3
Abstract
Introduction: Tuberculosis and Human Immunodeficiency Virus (HIV) co infection is becoming one of the most important public health issues in India. In some developing countries, 40% of all tuberculosis cases are attributed to HIV infection and in more than 50% of cases, tuberculosis is the first manifestation of HIV infection. Materials and methods: A cross sectional study was done among the in-patients of a tuberculosis ward in a tertiary care hospital in Eastern India. Fifty patients with HIV and tuberculosis infection of an extra pulmonary site, were included in the study. Results: A vast majority of the participants were young males. More than 80% were using intoxicants like alcohol or tobacco, 76% admitted exposure to commercial sex workers and 12% were intravenous drug users. Twenty five (50%) of the participants had disseminated tuberculosis, that is tubercular infection of more than one anatomical site. Maximum (62%) participants had tubercular infection of lymph nodes, followed by pleura, abdomen and central nervous system. Discussion and conclusions: The sociodemographic correlates of participants were similar to that seen in similar studies in other parts of the world. But in our study, tubercular lymphadenitis was the most common extra-pulmonary manifestation and proportion of disseminated tuberculosis cases was as high as 50%. Both these findings are different from studies from other parts of the world. These findings warrant a larger research study and programmatic changes to address issues of HIV/TB co infection.
Authors and Affiliations
Mathew Ninan| Department of Pulmonary Medicine, Pushpagiri Medical College, Tiruvalla, Kerala, India, Corresponding author email: communitymedicine@pushpagiri.in, Doye George| Department of Pulmonary Medicine, Pushpagiri Medical College, Tiruvalla, Kerala, India, P Sukumaran| Department of Pulmonary Medicine, Pushpagiri Medical College, Tiruvalla, Kerala, India, Gunanidhi Sahu| Department of Pulmonary Medicine, SCB Medical College, Cuttack, Orissa, India, RN Mania| Department of Pulmonary Medicine, SCB Medical College, Cuttack, Orissa, India, Philip Mathew| Department of Community Medicine, Pushpagiri Medical College, Tiruvalla, Kerala, India
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- EP ID EP11444
- DOI 10.5958/2319 - 5886.2015.00110.1
- Views 278
- Downloads 12
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