PERNICIOUS ANEMIA IN YOUNG: A CASE REPORT WITH REVIEW OF LITERATURE
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2015, Vol 4, Issue 4
Abstract
Pernicious anemia (PA) is characterized by Vitamin B12 deficiency which arises due to lack of intrinsic factor as a result of autoimmune destruction of gastric body mucosa and loss of gastric parietal cells. Generally it is considered as a disease of the elderly as its prevalence is 0.1% in general population and 1.9% in subjects over the age of 60 years. Pernicious anemia in age group below 30 years is less common (<4%). Clinical presentation of Pernicious anemia is insidious and varied ranging from subtle anemia to serious neurological manifestations with a future risk of developing neoplastic changes in stomach. It is considered as a “great pretender†because of its wide spectrum of clinical manifestations. But once diagnosed treatment is easy with parenteral replacement and maintenance of cobalamin.
Authors and Affiliations
Behera PK| Associate Professor, Department of Medicine, Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar, India, Behera PK Associate Professor, Department of Medicine, Kalinga Institute of Medical Sciences, Bhubaneswar, India Email: drpradip76@gmail.com, Tripathy KP| Professor, Department of Medicine, Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar, India, Panigrahi R| Associate professor, Dept. of Pathology, Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar, India, Tripathy S| Professor, Department of Medicine, Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar, India
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- EP ID EP11494
- DOI 10.5958/2319-5886.2015.00182.4
- Views 289
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