PHARMACOGNOSTICAL AND PRELIMINARY PHYTOCHEMICAL INVESTIGATIONS OF AERIAL PARTS OF TRICHODESMA INDICUM R. BR.
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 11
Abstract
Objective: This study was undertaken to carry out pharmacognostical studies and phytochemical studies on aerial parts of Trichodesma indicum R. Br belonging to the family Boraginaceae.Methods: The aerial parts of plant leaf and stem were evaluated for pharmacognostical studies such as macroscopy, microscopy, powder study, and quantitative microscopy. The powder was evaluated for proximate analysis like ash vale, extracting value, moisture content, swelling index, elemental analysis, fluorescence analysis, and preliminary phytochemical studies.Results: Transverse section of leaf of T. indicum R. Br. showed presence of covering trichomes with bulbous base upper and lower epidermis, collenchyma, prisms of calcium oxalate, vascular bundle and palisade cells. Surface preparation showed the presence of wavy epidermal cells, anomocytic stomata, anisocytic stomata, trichomes. Transverse section of Stem of Trichodesma indicum R. Br showed the presence of trichomes with, epidermis, hypodermis, cortex, xylem and pith. Powder study of aerial parts of T. indicum R. Br showed the presence of trichomes, xylem vessels, parenchyma, epidermal cells, fibres, calcium oxalate crystals. The powder of aerial parts was evaluated for proximate analysis such as ash value, extractive value, moisture content, total solid content, and the swelling index, which give idea about the presence of siliceous material, and amount of constituents extracted into different solvent. The elemental analysis of aerial parts showed that plant was free from heavy metal contamination i.e. arsenic, lead. The fluorescence analysis of plant powder showed that plant contains phenolic compounds. Qualitative chemical examination showed that the aerial parts of Trichodesma indicum R. Br, is credited with phytosterol, triterpenoids, tannins, phenolic compounds, carbohydrates, fixed oil, fatty acids mucilage.Conclusion: The study reveals specific identifying characteristics for the particular crude drug which will be of significant use in identification and control to adulteration of the raw drug and can serve as a reference for any further investigations.Â
Authors and Affiliations
Manani Lata M. , Saluja Ajay K. , Prajapati Parixit R.
VALIDATED SPECTROPHOTOMETRIC METHODS FOR DETERMINATION OF ENALAPRIL MALEATE IN PURE AND DOSAGE FORMS
Objective: Simple, sensitive, precise, reproducible and validated visible spectrophotometric methods have been developed for the determination of an angiotensin converting enzyme inhibitor (ACE) drug, namely enalapril ma...
ADULTICIDAL ACTIVITY OF BOTANICAL OILS BY IMPREGNATED PAPER ASSAY AGAINST CULEX QUINQUEFASCIATUS SAY
Objective: The present study was undertaken with the aim of finding out the efficacy of essential oils (EOs) as anti-mosquito agents for commercial purposes. Plant source insecticides as an alternative to chemical insect...
OXIDATIVE STRESS-BASED HEPATOTOXICITY OF DULOXETINE IN WISTAR RATS
Objective: Duloxetine, a selective serotonin and noradrenaline reuptake inhibitor used in major depressive disorders, urinary incontinence and diabetic peripheral neuropathic pain. It is reported to be associated with se...
STRUCTURAL AND FUNCTIONAL ANALYSIS OF AF9-MLL ONCOGENIC FUSION PROTEIN USING HOMOLOGY MODELING AND SIMULATION BASED APPROACH
Objective: AF9-MLL has been implicated in the pathogenesis of AML, New Therapeutic regimens are prerequisite for this category of hematological malignancy due to the poor prognosis. The experimental 3D structure of AF9-M...
AN ORAL FEED STRATEGY IN SHEEP FOR IMPROVED DIGESTIBILITY, NUTRIENT UTILIZATION AND METHANE MITIGATION
Objective: A trial was conducted to study the efficacy of herbal formulation Ruchamax (M/S Ayurvet Limited, India) on digestibility and nutrient utilization in Deccani sheep.Methods: 12 growing healthy Deccani sheep (5-6...