Phenylephrine Infusion vs. Ephedrine Infusion: Effect on Fetal Acidosis
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 5
Abstract
This randomized double blind study was started with an objective of comparing the fetal effects of two commonly used vasopressors – ephedrine and phenylephrine in elective caesarean section. Methods: One hundred patients were randomized into two groups to receive either 100 μg/ml phenylephrine (group-P, n=50) or 5mg/ml ephedrine (group-E, n=50). Immediately after spinal injection the study solution was started prophylactically in every patient at the rate of 60ml/hr. A predefined algorithm was used to adjust the infusion rate according to the systolic blood pressure (SBP). After delivery, arterial and venous blood samples were taken from a double-clamped segment of umbilical cord for immediate blood gas analysis with a blood gas analyser
Authors and Affiliations
Urvashi Yadav
Keywords
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