Plasmid Mediated Drug Resistance in Acinetobacter baumanii Isolated from Clinical Samples
Journal Title: IJAR-Indian Journal of Applied Research - Year 2015, Vol 5, Issue 5
Abstract
Acinetobacter baumannii is a nosocomial pathogen of increasing importance. Prevalence of the multidrug resistant phenotype (MDR) Acinetobacter baumannii has increased during the last decade worldwide. I-so lation, characterization of plasmids among resistant isolates are very important as they can be disseminated horizontally and contribute to global spread of resistance. Aim of the study to determine the antibiotic susceptibility of the isolates. Detection of plasmids from multidrug resistant A.baumanii by alkaline lysis method. A total of 107 clinically significant Acinetobacter species from clinical samples and plasmid extraction. A.baumanii from clinical samples were 73%,- mul tidrug resistant isolates were 69.2% and plasmid extracted were 59.5%. Awareness of plasmid mediated drug resistant and molecular profiling of these strains are important in current era of drug resistance.
Authors and Affiliations
Jayanthi. S, Ms. Renuka . B, Dr. Jeya. M, Mrs. Meena. N, Ms. Kurunchi C. Divya
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