Platelet Rich Fibrin -A Second Regeneration Platelet Concentrate and Advances in PRF
Journal Title: Indian Journal of Dental Advancements - Year 2015, Vol 7, Issue 4
Abstract
Regeneration is reconstitution of both hard and soft tissues in structure and function. Various modalities for regenerating of the tissues including bone grafts and substitutes, guided tissue regeneration (GTR) and the application of polypeptide growth factors (PGFs) to the surgical wound to promote periodontal regeneration. Autologus blood preparations are richest source for these polypeptide growth factors. Fibrin sealants act like as last step in the coagulation casacade.PRP is the first generation platelet concentrate. But the disadvantages of PRP are using of bovine thrombin which leads to allergic reaction. Choukron pioneered the Platelet rich fibrin (PRF).The present review highlights the preparation, advantages, limitations and various advances in PRF.
Authors and Affiliations
Pavan Kumar A, Vikram Reddy G, Raja Babu P, Jagadish Reddy G
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