Post-operative analgesic efficacy of fentanyl via different routes – A comparative study of nebulisation, intranasal and intravenous routes
Journal Title: International Archives of Integrated Medicine - Year 2016, Vol 3, Issue 6
Abstract
Background: Pain is main post operative adverse outcomes causing patient distress, prolonging hospital stay, and increasing the incidence of admissions after surgery. Study was done to assess and compare the post-operative analgesic effects of fentanyl via nebulisation, intranasal and intravenous routes to provide better analgesia, anxiolysis and sedation to the patient. Materials and methods: After approval from ethical committee of SPMC, Bikaner and written informed valid consent from patients, sixty patients of either sex belonging to ASA class I and II, were randomised into three group (Group I - Nebulised Fentanyl, Group II - Intranasal Fentanyl, Group III - Intravenous Fentanyl). With all aseptic precaution, subarachnoid block was instilated via 23/25 gauze spinal needle by injecting sufficient dose of bupivacaine heavy 5% to achieve an adequate sensory and motor block for the proposed surgery. When patient complained pain 1st time, fentanyl was given via nebulisation in group I, intranasal in group II, and intravenous in group III with dose 4 mcg/kg, 1.5 mcg/kg, 2 mcg/kg respectively. Patients were assessed for pain by VAS score. For statistical data, SPSS 10.0 software was used. Results: In present study, Ramsay sedation score, patient satisfaction score and duration of analgesia was better in group II as compared to group I and III. Group III had lesser time of onset of analgesia in comparison to group II and I respectively. Conclusion: On the basis of analgesic efficacy, we concluded that intranasal group was better than nebulisation and intravenous route.
Authors and Affiliations
Raghvendra Singh, Anita Pareek, Meera Kumari, Mohammad Yunus Khilji, Prashant Sirohiya
Keywords
Related Articles
- EP ID EP428790
- DOI -
- Views 106
- Downloads 0
Comparative study of complications following laparoscopic TEP versus TAPP versus open hernioplasty in inguinal hernia repair
Background: Hernia repairs, both inguinal and ventral/ incisional, are some of the most common surgeries performed in the world. Over the last 5 years, the field of hernia surgery has had a significant transformation tha...
A study on cardiac abnormalities in HIV patients and its relation with CD4 count and risk factors
Background: From the beginning of the AIDS epidemic, it was recognized first at autopsy and later by non-invasive techniques that HIV infection can cause cardiac abnormalities. Aim of the study: To assess the cardiac ab...
A rare case report of primary fallopian tube carcinoma in 40 year old female
Primary cancer of the fallopian tube is very rare. An average of 20 to 30 new cases are reported each year. The incidence of this cancer varies from 0.14 to 1.8% of all Gynecological cancers. It is possible that the true...
The role of ACE inhibitors in retarding the progression of non diabetic chronic kidney disease by controlling blood pressure and proteinuria
Lowering of blood pressure itself lowers urinary protein excretion rate and slows rate of GFR decline in chronic renal disease. There are data that suggests that ACE inhibitors improve glomerular barrier size selective f...
Community based cross sectional study on prevalence of risk factors of type 2 Diabetes Mellitus in adult population residing in urban area of Shahjahanpur, Uttar Pradesh
Diabetes is major health problem in India and the burden is rapidly increasing. The present study was conducted to find the prevalence of risk factors of diabetes in adult population residing in urban area of Shahjahanpu...