Pre-Clinical Modeling and Simulation of Radiofrequency Ablation in Human Lung Tumor
Journal Title: International Journal of Mechanical and Production Engineering Research and Development (IJMPERD ) - Year 2017, Vol 7, Issue 4
Abstract
Radio-frequency ablation (RFA) is a hyperthermia medical treatment modality, used to destroy the unwanted tissues in the human body. In this article, pre-clinical computational model has been demonstrated for attaining risk frees RFA of lung tumor. The objective of this study is, to investigate the effect of variable voltages on tissues, temperature distribution and voltage requirement for radiofrequency ablation in human lung tumor by simulation model, in order to find the effect of this technology, in realistic clinical treatment. A three-dimensional right human lung and tumor has been modelled from, 2D medical image data of lung tumor patient for performing temperature-controlled RFA. This study considers the effect of using single Trocar probes in the Radiofrequency Ablation, in the lung tumour RFA and the physics behind Radiofrequency (RF) heating is discussed, to establish hyperthermia treatment planning protocols for deep seated tumours inside complex lung anatomy. The whole process is done on COMSOL MULTYPHYSICS 5.2. The temperature distribution inside the tissue and at various points inside the tumour has been predicted, by integrating two different modules of COMSOL MULTIPHYSICS (the electric currents module and the bio-heat transfer module). The results show that, the effective tumor ablation essentially depends upon, exposure time and on voltage range. The study further evaluates the range of input voltage requirement, for attaining safe ablation of tumor tissue without damaging healthy tissue during temperature controlled RFA of lung tumor. The results from the current study may be useful for the clinical practitioners, by providing them guidelines and it could make the RFA more effective and reliable.
Authors and Affiliations
Gurwinder Singh, Mahakdeep Singh
Keywords
Related Articles
- EP ID EP240299
- DOI -
- Views 83
- Downloads 0
Remote Discrete-Time Model Reference Adaptive Control Of A Two-Wheeled Mobile Robot
This paper demonstrates a remote discrete model reference adaptive control for a two-wheeled mobile robot where actuators, sensors and controller are distributed and interconnected by a wireless communication. Since a ty...
Conceptual and Statistical Modeling for Identifying Linkages Among Supply Chain Strategy, Flexibility and Performance
In the current competitive and globalized market situation, the supply chain performance (SCP) and supply chain management (SCM) practices such as supply chain strategy (SCS), supply chain flexibility (SCF) are playing a...
Transient Analysis of Wind Turbine Blades
In this paper, transient analysis has been carried out on the blades to determine the strength of the blade for different blade materials, steel and composite materials ; E - Glass, carbon fibre and aramid fibre by apply...
Design of Pressure Vessel for Improvement of a System in a Process Unit
Vessels that carry, store, or get hold of fluids are known as pressure vessels. A pressure vessel is a containerwith a pressure differential between internal and outside. In the present paper, it has been discussed regar...
Defects of Communication Pipes from Plastic in Modern Civil Engineering
Plastic is an important material that is used in civil engineering. Communication pipes - one of the directions of use of plastic. The external environment affects the quality of the use of plastic pipes. Therefore it is...