Pre-Emptive Analgesic and Opioid Sparing Effect of Ketamine in Patients Undergoing Total Radical Mastectomy
Journal Title: International Journal of Research and Review - Year 2018, Vol 5, Issue 12
Abstract
Background: The present study has been undertaken to evaluate pre-emptive analgesic and opioid sparing effect of intravenous ketamine in patients undergoing total radical mastectomy. Method: Eighty female patients undergoing breast cancer surgery under general anesthesia, in a double-blinded, placebo controlled study were randomly divided into two groups of 40 patients each. Group K received ketamine 0.3mg/kg IV just before induction. Group C received normal saline as placebo. Result: Time to first analgesic dose (TFA) required was significantly delayed in ketamine as compared to placebo group. Statistically significant difference was seen in Visual analog score (VAS), Prince Henry score (PHS) and mean morphine consumption between ketamine and control group. Conclusion: This study proved that ketamine has a definitive role in reducing postoperative pain and has opioid sparing effect in patients undergoing modified radical mastectomy.
Authors and Affiliations
Shakti Datt Sharma
Keywords
Related Articles
- EP ID EP480937
- DOI -
- Views 95
- Downloads 0
A Study to Assess and Compare the Knowledge and Attitude Regarding Antenatal Care among Pregnant Women Consulting in Selected Urban and Rural Hospitals of Uttar Kannada District, Karnataka.
The antenatal care refers to care provided to the pregnant mother during their antenatal period which includes assessment, physical examination, obstetrical examination, antenatal advice which includes exercise, diet, ad...
Cooperative Values of Indonesian Folk Games: Efforts in the Nation Character Building
Indonesia has several folk games, such as kasti (baseball), lari goni (gunny run), engrang (bamboo feet), congklak (picking stones), patok lele (wood sticking), engklek (single foot jump), lompat tali (rope jump), kelere...
Critical Thinking Skill on Economics Subject of Students in SMA Negeri 1 Cikarang Pusat
Critical thinking is an important aspect that must be mastered by students in every subject. By having a good critical thinking skill, students can resolve the issue appropriately. The purpose of this research was to kno...
A Study of Etiological Factors of Pregnancy Related Acute Kidney Injury
Background: Pregnancy related acute kidney injury (PRAKI) contributes to 3.7% of overall acute kidney injury cases in Indian subcontinent. It is a major cause of maternal and fetal morbidity and mortality in developing c...
Formulation and Evaluation of Swellable Matrix Tablet Using Emerging Excipient Hibiscus Esculentus
The present study was undertaken with an objective to expound the swelling ability of Hibiscus esculentus Linn (HEP) powder and its capability to sustain the release of drug. The Okra mucilage was prepared using water...