Pre-operative Serum CEA and CA19-9 Levels in Patients with Gastric Cancer: A Single-Center Experience

Journal Title: Eastern Journal of Medical Sciences - Year 2018, Vol 3, Issue 3

Abstract

Introduction: To evaluate the preoperative CEA and CA19-9 levels and their association with clinicopathologic features and mortality. Methods: This retrospective study was conducted on patients who underwent gastric surgery due to gastric adenocarcinoma from 2008 to 2015. Preoperative serum CEA and CA19-9 levels were compared according to the TNM classification and survival data were compared. Results: A total of 335 patients were included in the study with the mean age of 66.1±11.0 years. CEA and CA19-0 positivity were 29.1% and 28.1%, respectively. According to the CEA groups, T stages of the cases were statistically significant (p = 0.013). The rates of T stage 1 in group 1 (CEA positive) were significantly higher than the group 2 (CEA negative) (p=0.007). According to the CA19-9 positivity; rate of stage 2 was significantly higher in the group 1 (CA19-9 positive) (p=0.001); however, rates of stage 2 and 3 were significantly higher in the group 2 (CA19-9 negative) (p=0.004 and p=0.007, respectively). Mortality information could be accessed for 309 cases and 108 deaths (36%) were observed. The mean survival time was 45.21±2.42 months. No significant difference was observed between the groups (p>0.05). Conclusion: Patients with higher levels of CEA and CA19-9 seem to have higher grades of gastric cancer. However, CEA and CA19-9 level does not seem to be in association in our study population.

Authors and Affiliations

Ibrahim Atak, Serkan FatihYegen, Tuba Atak, Alaattin Guler, Lutfi Polat, Veysi Samsa

Keywords

Related Articles

Development and Validation of a Scale for Measuring Family Happiness

Objective: We aimed to develop a subjective family happiness scale and analyzed its validation and reliability. Methods: To develop, a scale for measuring subjective family happiness, an item pool was created. A 19-item...

Internalized Homophobia and Coming out Process in Adolescence: A Case Report

For homosexual individuals, on the basis of self-directed homophobic attitudes and difficulties experienced during the coming out process, their society’s heterosexist and homophobic attitudes are specifically considered...

Chromobacterium violaceum – an unusual pathogen. Perspectives to ponder!!

Human infection due to Chromobacterium violaceum is rare, even though the bacteria are ubiquitous in distribution. Without appropriate antimicrobial therapy, the consequences can be rapidly fatal if septicemia sets in. B...

Assessment of Knowledge and Behaviour of Pharmacy Services Students in Vocational School Of Health Services for Rational Drug Use

Objective: To evaluate the knowledge and behaviour of the students about the rational drug use studying in the pharmacy services program in Vocational School of Health Services (VSHS). Methods: This cross-sectional study...

Prediction of Low Factor V Levels in Patients with Herbal Medicine Related Acute Liver Injury

Background: Prior epidemiologic studies predicted a rapid rise in herbal medicine-related acute liver injury (HILI) and liver transplantation (LT) as trading of traditional herbal medicine drugs is expanded. HILI is the...

Download PDF file
  • EP ID EP527181
  • DOI -
  • Views 66
  • Downloads 0

How To Cite

Ibrahim Atak, Serkan FatihYegen, Tuba Atak, Alaattin Guler, Lutfi Polat, Veysi Samsa (2018). Pre-operative Serum CEA and CA19-9 Levels in Patients with Gastric Cancer: A Single-Center Experience. Eastern Journal of Medical Sciences, 3(3), 39-43. https://www.europub.co.uk/articles/-A-527181