Precancerous conditions in gynecology
Journal Title: Postępy Nauk Medycznych - Year 2013, Vol 26, Issue 7
Abstract
Precancerous conditions in gynecologic oncology are the changes where malignant neoplasms occur more frequently than in the healthy tissue of female genital tract.Vulvar and vaginal precancerous leasions occure in any age of women. Signifficant increase of their occurence is observed in relatively young patients (i.e. below 40 yrs.). Ethiopatogenic factors are: HPV infections, chronic inflammation, altered tissue trophy. Diagnostisc of vulvar and vaginal leasions is always based on specimen pathological examination. Treatment depends on the pathologic result as well as clinical status of the patient.Cervical cancer has been a serious epidemiological problem for many years in Poland. The number of cases gradually decreases but it still remains at too high rate.Cervical Intraepithelial Neoplasia (CIN) generally appears in the transformation zone (transient zone), nearby the external orifice. Leasions may progress into invasive cancer or can stay fixed for many years. Among numerous well known cervical cancer development risk factors, the most significant is the infection of human papilloma virus, especially with typical, high potential oncogenic virus. Treatment depends on severity of the changes. The majority of uterine carcinoma is preceeded by abnormal proliferation.The vast maiority of endometrial cancers is preceeded by pathologic hyperplasia with atypia of the endometrium. However it is noteworthy, that approx. 1.6% of endometrial carcinoma is not proceeded by atypia of the endometrium. In case of endometrial hyperplasia with atypia the progression to endometrial carcinoma is observed in 23-56% of all cases. The mode of endometrial hyperplasia treatment depends on precise type of the leasion.
Authors and Affiliations
Katarzyn Wójcik-Krowiranda, Tomasz Michalski, Andrzej Bieńkiewicz
Keywords
Related Articles
- EP ID EP54749
- DOI -
- Views 142
- Downloads 0
Autosomal dominant polycystic kidney disease (ADPKD) – targets of pharmacotherapy and extrarenal complications
Autosomal dominant polycystic kidney disease (ADPKD) is hereditary cystic disorderwith predominantly renal manifestation (large kidneys, flank pain, haematuria, hypertensionand renal insufficiency). Some patients also pr...
Hereditary spherocytosin in children – diagnosis and treatment
Congenital hemolytic anemia are group of diseases characterized by shortening of the survival time of red blood cells. In clinical picture various degrees of anemia, jaundice and splenectomy are observed. One of them is...
An assessment of the frequency of lymphocytes with IL-4 intracellular expression and IL-4 concentration in the plasma of patients with chronic lymphocytic leukemia depending on the occurrence of Epstein-Barr virus DNA in peripheral blood mononuclear cells
Introduction. Epstein-Barr virus (EBV), also referred to as human herpesvirus 4 (HHV-4), is the first identified human virus with documented involvement in carcinogenesis. Chronic lymphocytic leukemia (CLL) is a neoplast...
Bilateral adrenal tumors with subclinical hypercortisolemia. To operate or observe?
According to various sources, subclinical hypercortisolemia caused by benign adrenal tumors shows unquestionable indication to adrenalectomy. However, some works assessing effects of such surgery revealed no clinical ben...
Zastosowanie biopsji cienkoigłowej w diagnostyce guzków tarczycy
Wstęp. Biopsja cienkoigłowa (FNA) jest inwazyjną, jednak stosunkowo prostą i niedrogą procedurą medyczną łatwo wykonywaną w warunkach przychodni bez konieczności hospitalizacji pacjenta. Ma zastosowanie głównie w diagnoz...