Predictive factors of infectious complications following Percutaneous Nephrolithitomy-An Institutional Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 5
Abstract
Objective: To determine the predictors of infectious complications following percutaneous nephrolithotomy (PCNL) in a prospective study. Materials and Methods: A total of 120 patients with renal or upper ureteric calculi who underwent PCNL between January 2016 and December 2017 were included in the study. Infectious complications included febrile urinary tract infection and septicemia. The patients were divided into Group A and B depending on whether they developed or did not develop infectious complications. Patient, stone, renal, and procedure‑ related factors were compared between the two groups. Results: There was no significant (P > 0.05) difference among age (39.5±18.3vs 40.76±19.4 ) and sex between both the groups. The patients in Group A were found to have significantly higher incidence of renal failure (37.5% vs 6.73%, P = 0.00022), diabetes mellitus ([5 (31.52%) vs. 12 (11.53%), P = 0.035]), previous PCN tube placement (4 [25%] vs. 6 [5.8%] P = 0.0096), mean number of punctures (1.88 ± 0.7 vs. 1.4 ± 0.38, P = 0.0001), and mean duration of surgery (101.56±21.02 vs. 87±18.76, P = 0.0052) than Group B. The multivariate binary logistic regression analysis revealed that patients with renal failure (serum creatinine >1.4 mg/dl), staghorn stone, higher number of puncture, and longer duration of surgery were found to be significant factors associated with infectious complications Conclusion: Post‑ PCNL infectious complications were found to be more common in patients with renal failure, diabetes mellitus, preoperative PCN placement, staghorn calculi, severe HDN, multiple punctures, and prolonged duration of surgery.
Authors and Affiliations
J. V. S. Prakash, Venkatesh Ulaganathan, Arasi . K. V, Natarajan . V
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